Table 1.

Clinical and Laboratory Data of Patients With Hereditary Spherocytosis

PatientsAgeHemoglobinMCVMCHCReticulocytesSpectrin/band 3*2.1/band 3Relative Protein Content
(yr)g/dLFLg/dL×109/L
I.1 58 13.4 87 32.9 416.5 1.28 0.25 78% Band 3 
II.1 36 12.4 91 32.5 544.70 1.34 0.28 75% Band 3 
II.2 32 12.7 87 33.3 543.12 1.26 0.25 79% Band 3 
3 38 14.7 85 35.0 137.80 1.42 0.30 70% Band 3 
4 32 14.5 92 32.1 98.20 1.26 0.26 79% Band 3 
5 20 13.7 78 35.6 59.28 1.00 0.14 70% Ankyrin 
PatientsAgeHemoglobinMCVMCHCReticulocytesSpectrin/band 3*2.1/band 3Relative Protein Content
(yr)g/dLFLg/dL×109/L
I.1 58 13.4 87 32.9 416.5 1.28 0.25 78% Band 3 
II.1 36 12.4 91 32.5 544.70 1.34 0.28 75% Band 3 
II.2 32 12.7 87 33.3 543.12 1.26 0.25 79% Band 3 
3 38 14.7 85 35.0 137.80 1.42 0.30 70% Band 3 
4 32 14.5 92 32.1 98.20 1.26 0.26 79% Band 3 
5 20 13.7 78 35.6 59.28 1.00 0.14 70% Ankyrin 

Abbreviations: MCV, mean corpuscular volume; MCHC, mean corpuscular hemoglobin concentration.

*

Ratio of spectrin/band 3 in 30 normal controls: x̄ ± SD = 1.0 ± 0.07 (0.92 to 1.10).

Ratio of ankyrin (2.1)/band 3 in 30 normal controls: x̄ ± SD = 0.20 ± 0.02 (0.17 to 0.24).

Splenectomized.

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