Table 1. IL-6–Induced Differentiation of... | American Society of Hematology

Table 1.

IL-6–Induced Differentiation of M1, M1neo, and M1HOX-B8

Clone	IL-6	Cell Type (%)^*			Fc^*	C3^*	Cell No.^*
	(ng/mL)	Blast	Inter	Mat	(%)	(%)	(10⁶/mL)
M1	—	99	1	0	<1	<1	1.93
	5	46	52	2	20	10	1.29
	50	0	29	71	49	72	0.37
M1neo-9	—	99	1	0	<1	<1	2.01
	5	52	45	3	21	12	1.39
	50	0	32	68	52	73	0.34
M1HOX-B8/2	—	99	1	0	<1	<1	2.01
	5	47	49	4	19	13	1.32
	50	0	28	72	54	72	0.30
M1HOX-B8/3	—	99	1	0	<1	<1	1.91
	5	51	46	3	22	10	1.35
	50	0	33	67	54	64	0.29

Clone	IL-6	Cell Type (%)^*			Fc^*	C3^*	Cell No.^*
	(ng/mL)	Blast	Inter	Mat	(%)	(%)	(10⁶/mL)
M1	—	99	1	0	<1	<1	1.93
	5	46	52	2	20	10	1.29
	50	0	29	71	49	72	0.37
M1neo-9	—	99	1	0	<1	<1	2.01
	5	52	45	3	21	12	1.39
	50	0	32	68	52	73	0.34
M1HOX-B8/2	—	99	1	0	<1	<1	2.01
	5	47	49	4	19	13	1.32
	50	0	28	72	54	72	0.30
M1HOX-B8/3	—	99	1	0	<1	<1	1.91
	5	51	46	3	22	10	1.35
	50	0	33	67	54	64	0.29

Abbreviations: inter, intermediate; mat, mature.

Determined 3 days after the cells were seeded at a density of 0.15 × 10⁶. Four M1neo clones and six M1HOX-B8 clones were analyzed, and data is presented for representative clones. All values represent the mean of three independent determinations with standard deviations up to 15% (ie, 11% ± 1.6%).

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