Platelet Adhesion Under Flow Conditions
| Surface . | Shear Rate (s−1) . | Coverage . |
|---|---|---|
| Collagen I | 300 | 15.2 ± 2.3 (n = 4) |
| CRP 1 | 300 | 0* (n = 12) |
| CRP 1-XL | 300 | 0* (n = 12) |
| CRP 2 | 300 | 0* (n = 12) |
| CRP 2-XL | 300 | 0* (n = 12) |
| Collagen I | 50 | 4.1 ± 1.5 (n = 3) |
| CRP 1 | 50 | 0 (n = 5) |
| CRP 2 | 50 | 0 (n = 5) |
| Surface . | Shear Rate (s−1) . | Coverage . |
|---|---|---|
| Collagen I | 300 | 15.2 ± 2.3 (n = 4) |
| CRP 1 | 300 | 0* (n = 12) |
| CRP 1-XL | 300 | 0* (n = 12) |
| CRP 2 | 300 | 0* (n = 12) |
| CRP 2-XL | 300 | 0* (n = 12) |
| Collagen I | 50 | 4.1 ± 1.5 (n = 3) |
| CRP 1 | 50 | 0 (n = 5) |
| CRP 2 | 50 | 0 (n = 5) |
Data are expressed as the percentage of surface covered by platelets. Peptides were sprayed at a concentration of 10 μg/cm2 on Thermanox coverslips. Collagen I was as in Table 1. Values are the mean ± SD (n = number of evaluated coverslips).
Peptides were also sprayed at 10 μg/cm2 on Denhardt-coated glass coverslips and micro-sprayed at a concentration of 300 μg/cm2 on glass coverslips as mentioned in the Materials and Methods.