Impact of Clinical and Disease Characteristics on Lymphoma Cell Content in BM, PB, and mPB
Clinical Parameters . | Two-Tailed P Values Versus the No. of Lymphoma Cells (QC-PCR) in . | ||
---|---|---|---|
BM (n = 37) . | PB (n = 26) . | Mobilized PB (n = 17) . | |
Age | |||
≤45 v>45 | .703 | .271 | .769 |
Sex | |||
Male vfemale | .801 | .783 | .922 |
Stage | |||
III vIV | .208 | .094 | .460 |
Histology | |||
Follicular vdiffuse | .041 | .929 | .034 |
Remission status | |||
CR v PR | .964 | .513 | .207 |
No. of remissions | |||
1* v ≥2 | .397 | .126 | .365 |
BM infiltration† at any time | |||
Yes vno | .015 | .012 | .148 |
BM infiltration† at harvest | |||
Yes v no | .082 | .136 | .30 |
Clinical Parameters . | Two-Tailed P Values Versus the No. of Lymphoma Cells (QC-PCR) in . | ||
---|---|---|---|
BM (n = 37) . | PB (n = 26) . | Mobilized PB (n = 17) . | |
Age | |||
≤45 v>45 | .703 | .271 | .769 |
Sex | |||
Male vfemale | .801 | .783 | .922 |
Stage | |||
III vIV | .208 | .094 | .460 |
Histology | |||
Follicular vdiffuse | .041 | .929 | .034 |
Remission status | |||
CR v PR | .964 | .513 | .207 |
No. of remissions | |||
1* v ≥2 | .397 | .126 | .365 |
BM infiltration† at any time | |||
Yes vno | .015 | .012 | .148 |
BM infiltration† at harvest | |||
Yes v no | .082 | .136 | .30 |
Differences in the number of lymphoma cells, as measured by our QC-PCR assay, for each clinical parameter were analyzed with Mann-Whitney U Test. Two-tailed P values were corrected for ties. Statistically significant differences (P < .05) are represented in bold.
All patients in first remission failed to achieve a complete remission after completing the initial chemotherapy.
Identified on pathologic examination.