Table 2.

Impact of Clinical and Disease Characteristics on Lymphoma Cell Content in BM, PB, and mPB

Clinical ParametersTwo-Tailed P Values Versus the No. of Lymphoma Cells (QC-PCR) in
BM (n = 37)PB (n = 26)Mobilized PB (n = 17)
Age 
 ≤45 v>45 .703 .271 .769 
Sex 
 Male vfemale .801 .783 .922 
Stage 
 III vIV .208 .094 .460 
Histology 
 Follicular vdiffuse .041 .929 .034 
Remission status 
 CR v PR .964 .513 .207 
No. of remissions 
 1* v ≥2 .397 .126 .365 
BM infiltration† at any time 
 Yes vno .015 .012 .148 
BM infiltration† at harvest 
 Yes v no .082 .136 .30 
Clinical ParametersTwo-Tailed P Values Versus the No. of Lymphoma Cells (QC-PCR) in
BM (n = 37)PB (n = 26)Mobilized PB (n = 17)
Age 
 ≤45 v>45 .703 .271 .769 
Sex 
 Male vfemale .801 .783 .922 
Stage 
 III vIV .208 .094 .460 
Histology 
 Follicular vdiffuse .041 .929 .034 
Remission status 
 CR v PR .964 .513 .207 
No. of remissions 
 1* v ≥2 .397 .126 .365 
BM infiltration† at any time 
 Yes vno .015 .012 .148 
BM infiltration† at harvest 
 Yes v no .082 .136 .30 

Differences in the number of lymphoma cells, as measured by our QC-PCR assay, for each clinical parameter were analyzed with Mann-Whitney U Test. Two-tailed P values were corrected for ties. Statistically significant differences (P < .05) are represented in bold.

*

All patients in first remission failed to achieve a complete remission after completing the initial chemotherapy.

Identified on pathologic examination.

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