Analysis of Dermal Mast Cells in Various Compound Heterozygous Mice
Genotype . | Mast Cells/mm2 . |
---|---|
+/+ | 27.14 ± 3.31 |
hSCF 220/+ | 26.86 ± 4.26 |
W/+ | 23.71 ± 2.62 |
Sl/+ | 11.60 ± 2.56 |
hSCF 220/W | 4.10 ± 1.53* |
hSCF 220/Sl | 3.84 ± 1.40* |
Genotype . | Mast Cells/mm2 . |
---|---|
+/+ | 27.14 ± 3.31 |
hSCF 220/+ | 26.86 ± 4.26 |
W/+ | 23.71 ± 2.62 |
Sl/+ | 11.60 ± 2.56 |
hSCF 220/W | 4.10 ± 1.53* |
hSCF 220/Sl | 3.84 ± 1.40* |
wt; +/+, hemizygous hSCF 220; hSCF 220/+, W; W/+, Sl; Sl/+, and compound heterozygous mice generated by mating hSCF 220/+ by W/+ (hSCF 220/W) and hSCF 220/+ by Sl/+ (hSCF 220/Sl) were analyzed for total skin mast cells as described in the Materials and Methods section. Total mast cell number per square millimeters of skin for various mice are shown as the mean ± SEM. At least 6 mice were analyzed from each group.
P < .01 hSCF 220/Sl, hSCF 220/W v wt, hSCF 220/+, Sl/+, W/+.