Table 2.

Effect of chCCL-1 on Survival in Mice Bearing Human Lymphoma

Experiment TumorInitiation of TherapyTreatmentMean DODRange
 
Michel (ALCL) 3 d msIgG1 31 30-32 
  Lym-2 38 31-60 
Raji (Burkitt's) 3 d msIgG1 39 28-45 
  Anti-CD40 72 57-91* 
  Lym-2 72 37-91* 
RL (Diffuse large cell) 3 d msIgG1 70 58-81 
 3 d Lym-2 98 75-220* 
Daudi (Burkitt's) 3 d msIgG1 37 34-50 
 3 d chCLL-1 84 40-104* 
Experiment TumorInitiation of TherapyTreatmentMean DODRange
 
Michel (ALCL) 3 d msIgG1 31 30-32 
  Lym-2 38 31-60 
Raji (Burkitt's) 3 d msIgG1 39 28-45 
  Anti-CD40 72 57-91* 
  Lym-2 72 37-91* 
RL (Diffuse large cell) 3 d msIgG1 70 58-81 
 3 d Lym-2 98 75-220* 
Daudi (Burkitt's) 3 d msIgG1 37 34-50 
 3 d chCLL-1 84 40-104* 

Mice were treated with 2 μg of Lym-2, anti-CD40, chCCL-1, or msIgG1 as described in the Materials and Methods.

Abbreviations: DOD, day of death; ALCL, anaplastic large-cell lymphoma.

*

P < .01.

P < .005.

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