Effects of Cytokine Manipulations on Survival After BCL1 Challenge in BALB/c and B10.D2
| Mouse . | Group . | Treatment . | Survival (days) . | P Value . |
|---|---|---|---|---|
| BALB/c | 1 | none | 35.8 ± 1.3 | |
| 2 | rmIL-12 | 45.2 ± 7.0 | .018 | |
| 3 | 11B11 | 36.4 ± 1.8 | .565 | |
| 4 | rmIL-12 + 11B11 | 37.6 ± 6.9 | .581 | |
| 5 | rmIL-12 + anti-NK | 37.6 ± 5.4 | .487 | |
| 6 | anti-NK | 29.4 ± 1.7 | .0001 | |
| B10.D2 | 7 | none | >100 | |
| 8 | XMG1.2 | >100 | ||
| 9 | anti-NK | >100 |
| Mouse . | Group . | Treatment . | Survival (days) . | P Value . |
|---|---|---|---|---|
| BALB/c | 1 | none | 35.8 ± 1.3 | |
| 2 | rmIL-12 | 45.2 ± 7.0 | .018 | |
| 3 | 11B11 | 36.4 ± 1.8 | .565 | |
| 4 | rmIL-12 + 11B11 | 37.6 ± 6.9 | .581 | |
| 5 | rmIL-12 + anti-NK | 37.6 ± 5.4 | .487 | |
| 6 | anti-NK | 29.4 ± 1.7 | .0001 | |
| B10.D2 | 7 | none | >100 | |
| 8 | XMG1.2 | >100 | ||
| 9 | anti-NK | >100 |
All mice in each group were injected with a lethal dose of 10,000 BCL1 intraperitoneally on day 0. P values represent comparisons against group 1 (control group). Values represent mean ± standard deviation of 10 mice in each group. This is a representative experiment of two separate experiments.