Table 1.

Kinetics of Cell Death Induced by Soluble or Plastic-Immobilized 38.13 Anti-CD77 MoAb and DA4.4 Anti-IgM MoAb

% of Cell Viability
5 h10 h20 h48 h
Anti-CD77 83 ± 6 82 ± 5 77 ± 5 74 ± 6 
Anti-IgM 80 ± 5 81 ± 7 74 ± 4 65 ± 6 
RARa 75 ± 7 77 ± 7 78 ± 7 82 ± 6 
RARa + α-CD77 79 ± 3 67 ± 7 30 ± 5 39 ± 7 
RAM-G 81 ± 2 82 ± 8 77 ± 5 77 ± 5 
RAM-G + α-IgM 58 ± 7 47 ± 6 5 ± 3 
% of Cell Viability
5 h10 h20 h48 h
Anti-CD77 83 ± 6 82 ± 5 77 ± 5 74 ± 6 
Anti-IgM 80 ± 5 81 ± 7 74 ± 4 65 ± 6 
RARa 75 ± 7 77 ± 7 78 ± 7 82 ± 6 
RARa + α-CD77 79 ± 3 67 ± 7 30 ± 5 39 ± 7 
RAM-G 81 ± 2 82 ± 8 77 ± 5 77 ± 5 
RAM-G + α-IgM 58 ± 7 47 ± 6 5 ± 3 

CD77+ MUTU I BL cells were cultured for various times with anti-CD77 (38.13; 10 μg/mL) or anti-human IgM (DA4.4; 5 μg/mL) MoAb or were incubated in Petri dishes that had been previously coated with: RARa; RARa and 38.13 MoAb (RARa + α-CD77); RAM-G; and RAM-G and DA4.4 MoAb (RAM-G + α-IgM).

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