Complement-Dependent Cytotoxicity
| Antibody (1 μg/mL) . | Complement Dilution . | |||
|---|---|---|---|---|
| . | None . | 1:100 . | 1:20 . | 1:5 . |
| None | 1.0 ± 1.6 | 1.2 ± 0.5 | 0.4 ± 2.1 | 0.8 ± 0.9 |
| Control IgG | 0.5 ± 1.4 | 0.9 ± 1.6 | 0.6 ± 0.5 | 0.1 ± 1.0 |
| Anti-HM1.24 | ||||
| F(ab′)2 | 0.2 ± 0.5 | 1.1 ± 1.5 | 0.5 ± 0.9 | 0.5 ± 0.6 |
| Anti-HM1.24 IgG | 1.3 ± 1.1 | 3.8 ± 0.6 | 16.6 ± 1.0 | 68.6 ± 2.8 |
| Antibody (1 μg/mL) . | Complement Dilution . | |||
|---|---|---|---|---|
| . | None . | 1:100 . | 1:20 . | 1:5 . |
| None | 1.0 ± 1.6 | 1.2 ± 0.5 | 0.4 ± 2.1 | 0.8 ± 0.9 |
| Control IgG | 0.5 ± 1.4 | 0.9 ± 1.6 | 0.6 ± 0.5 | 0.1 ± 1.0 |
| Anti-HM1.24 | ||||
| F(ab′)2 | 0.2 ± 0.5 | 1.1 ± 1.5 | 0.5 ± 0.9 | 0.5 ± 0.6 |
| Anti-HM1.24 IgG | 1.3 ± 1.1 | 3.8 ± 0.6 | 16.6 ± 1.0 | 68.6 ± 2.8 |
Data represent the mean ± SD of the percentage of Cr-release.