Table 8.

Relative Risks of Relapse, Treatment Failure or Death after ABMT for AML in CR1

Poor Prognostic FactorRR (95% CI)P
Relapse Poor cytogenetics 2.19 (1.89-2.51) .003 
 Not FAB M3 1.91 (1.78-2.07) .04 
Treatment failure Poor cytogenetics 1.83 (1.60-2.09) .01 
 Not FAB M3 2.35 (2.17-2.51) .006 
Death Not FAB M3 2.82 (2.57-3.05) .004 
 Short int CR-BMT 2.73 (1.95-3.77) .01 
Poor Prognostic FactorRR (95% CI)P
Relapse Poor cytogenetics 2.19 (1.89-2.51) .003 
 Not FAB M3 1.91 (1.78-2.07) .04 
Treatment failure Poor cytogenetics 1.83 (1.60-2.09) .01 
 Not FAB M3 2.35 (2.17-2.51) .006 
Death Not FAB M3 2.82 (2.57-3.05) .004 
 Short int CR-BMT 2.73 (1.95-3.77) .01 

Adjustment was made for WBC at diagnosis, bone marrow purging, and year of ABMT.

Abbreviations: ABMT, autologous bone marrow transplantation; AML, acute myeloblastic leukemia; CR1, first complete remission; RR, relative risk; CI, confidence interval; FAB, French-American-British classification; int CR-BMT, time interval from complete remission to bone marrow transplantation.

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