Patient Characteristics
| . | AlloBMT . | ABMT . | P . |
|---|---|---|---|
| Age, median (range), yrs | 32.1 (16-51) | 39.5 (17-59) | <.001 |
| Sex, M/F | 257/243 | 279/220 | |
| WBC at diagnosis, ×109/L | 10.6 (<1-296) | 15 (1-238) | .02 |
| FAB classification, n (%) | |||
| M1 | 62 (12) | 88 (18) | |
| M2 | 162 (32) | 168 (34) | |
| M3 | 66 (13) | 60 (12) | |
| M4 | 111 (22) | 97 (19) | |
| M5 | 63 (13) | 58 (12) | |
| M6 | 8 (2) | 14 (3) | |
| M7 | 3 (1) | 8 (2) | |
| Unclassified | 25 (5) | 6 (1) | |
| Time to CR, median, days | 42 (22-165) | 41 (15-363) | |
| Median time diagnosis-BMT, days | 145 (70-456) | 181 (80-625) | <.001 |
| Median time CR-BMT | 87 (10-358) | 126 (15-642) | <.001 |
| Conditioning regimens | |||
| TBI | 381 | 263 | |
| Busulfan | 112 | 181 | |
| Other | 2 | 54 | |
| UNK | 5 | 1 | |
| GVHD prophylaxis, n | |||
| MTX | 16 | ||
| CsA | 104 | ||
| MTX + CsA | 260 | ||
| T-cell depletion | 120 | ||
| Purging | 88 |
| . | AlloBMT . | ABMT . | P . |
|---|---|---|---|
| Age, median (range), yrs | 32.1 (16-51) | 39.5 (17-59) | <.001 |
| Sex, M/F | 257/243 | 279/220 | |
| WBC at diagnosis, ×109/L | 10.6 (<1-296) | 15 (1-238) | .02 |
| FAB classification, n (%) | |||
| M1 | 62 (12) | 88 (18) | |
| M2 | 162 (32) | 168 (34) | |
| M3 | 66 (13) | 60 (12) | |
| M4 | 111 (22) | 97 (19) | |
| M5 | 63 (13) | 58 (12) | |
| M6 | 8 (2) | 14 (3) | |
| M7 | 3 (1) | 8 (2) | |
| Unclassified | 25 (5) | 6 (1) | |
| Time to CR, median, days | 42 (22-165) | 41 (15-363) | |
| Median time diagnosis-BMT, days | 145 (70-456) | 181 (80-625) | <.001 |
| Median time CR-BMT | 87 (10-358) | 126 (15-642) | <.001 |
| Conditioning regimens | |||
| TBI | 381 | 263 | |
| Busulfan | 112 | 181 | |
| Other | 2 | 54 | |
| UNK | 5 | 1 | |
| GVHD prophylaxis, n | |||
| MTX | 16 | ||
| CsA | 104 | ||
| MTX + CsA | 260 | ||
| T-cell depletion | 120 | ||
| Purging | 88 |
Abbreviations: AlloBMT, allogeneic bone marrow transplantation; ABMT, autologous bone marrow transplantation; WBC, white blood cell count; FAB, French-American-British; CR, complete remission; TBI, total body irradiation; UNK, unknown; GVHD, graft-versus-host disease; MTX, methotrexate; CsA, cyclosporin A.