Comparison of Blood Differentials and ICSBP-Transcript Numbers in Selected CML Patients Without or Under IFN-α Treatment
| Patient No. . | IFN-α Therapy . | Leukocytes (×103/μL) . | Lymphocytes (%) . | Blasts (%) . | ICSBP-mRNA Level* . |
|---|---|---|---|---|---|
| 1 | − | 137.0 | 0 | 15 | 0.000 |
| 2 | − | 2.7 | 13 | 0 | 0.071 |
| 3 | − | 16.6 | 11 | 1 | 0.150 |
| 4 | − | 4.6 | 10 | 0 | 0.010 |
| 5 | − | 453.0 | 2 | 4 | 0.000 |
| 6 | − | 7.8 | 17 | 1 | 0.170 |
| 7 | + | 3.4 | 15 | 0 | 0.718 |
| 8 | + | 2.3 | 49 | 0 | 0.510 |
| 9 | + | 8.8 | 8 | 0 | 0.710 |
| 10 | + | 5.7 | 18 | 0 | 0.416 |
| 11 | + | 6.8 | 15 | 0 | 0.569 |
| Patient No. . | IFN-α Therapy . | Leukocytes (×103/μL) . | Lymphocytes (%) . | Blasts (%) . | ICSBP-mRNA Level* . |
|---|---|---|---|---|---|
| 1 | − | 137.0 | 0 | 15 | 0.000 |
| 2 | − | 2.7 | 13 | 0 | 0.071 |
| 3 | − | 16.6 | 11 | 1 | 0.150 |
| 4 | − | 4.6 | 10 | 0 | 0.010 |
| 5 | − | 453.0 | 2 | 4 | 0.000 |
| 6 | − | 7.8 | 17 | 1 | 0.170 |
| 7 | + | 3.4 | 15 | 0 | 0.718 |
| 8 | + | 2.3 | 49 | 0 | 0.510 |
| 9 | + | 8.8 | 8 | 0 | 0.710 |
| 10 | + | 5.7 | 18 | 0 | 0.416 |
| 11 | + | 6.8 | 15 | 0 | 0.569 |
Abbreviations: −, no IFN-α treatment; +, under IFN-α therapy.
Relative ICSBP expression is displayed as arbitrary value, calculated as ratio of the integrated optical densities (IntOD) ofICSBP- to β-actin-transcript numbers.