Table 1.

Acute Leukemia Evolution and Survival Time of MDS Patients Within Subgroups Identified by Different Scoring Systems and the FAB Classification

Risk Category
LowIntermediateHigh
A. Median survival (mo) 
Prognostic system 
Mufti 32.7  17.6  11.9 
Sanz 64.3  14.4  11.9 
Goasquen 50.1 32.7  11.9 15.1 
Morra 39.6 12.3  15.7 11.9 
Morel 62.3  16.8  12.4 
IPSS 40.6 25.8  14.9 10.4 
FAB 52.1  17.1  10.5 
B. 25% acute leukemia evolution (mo) 
Prognostic system 
Mufti NR  8.3  6.2 
Sanz NR  9.5  4.2 
Goasguen NR 23.6  6.4 8.9 
Morra 18.5 7.0  10.6 5.0 
Morel NR  8.8  6.0 
IPSS NR 17.7 8.6  5.0 
FAB NR  9.2  4.7 
Risk Category
LowIntermediateHigh
A. Median survival (mo) 
Prognostic system 
Mufti 32.7  17.6  11.9 
Sanz 64.3  14.4  11.9 
Goasquen 50.1 32.7  11.9 15.1 
Morra 39.6 12.3  15.7 11.9 
Morel 62.3  16.8  12.4 
IPSS 40.6 25.8  14.9 10.4 
FAB 52.1  17.1  10.5 
B. 25% acute leukemia evolution (mo) 
Prognostic system 
Mufti NR  8.3  6.2 
Sanz NR  9.5  4.2 
Goasguen NR 23.6  6.4 8.9 
Morra 18.5 7.0  10.6 5.0 
Morel NR  8.8  6.0 
IPSS NR 17.7 8.6  5.0 
FAB NR  9.2  4.7 

For the FAB classification: low risk, RA + RARS; intermediate risk RAEB; high risk, RAEB-t + CMML.

Abbreviation: NR, not reached.

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