Results of Analyses of Risk of First Stroke in SS Patients
| Predictor . | Relative Risk . | 95% CI . | PValue . |
|---|---|---|---|
| A. Infarctive stroke (final multivariate model: five predictors significant at P < .05) | |||
| Prior TIA | 56.0 | 12.0, 285 | <.001 |
| Steady-state Hb | 1.85 per 1 g/dL* decrease | 1.32, 2.59 | <.001 |
| Acute chest syndrome within 2 weeks prior | 7.03 | 1.85, 26.7 | .001 |
| Acute chest syndrome rate | 2.39 per event/yr | 1.27, 4.48 | .005 |
| Systolic blood pressure | 1.31 per 10 mm Hg increase | 1.03, 1.67 | .033 |
| B. Hemorrhagic stroke (final multivariate model: two predictors significant atP < .05) | |||
| Steady-state Hb | 1.61 per 1 g/dL* decrease | 1.11, 2.35 | .013 |
| Steady-state leukocyte count | 1.94 per 5 × 109/L increase | 1.73, 2.18 | .026 |
| Predictor . | Relative Risk . | 95% CI . | PValue . |
|---|---|---|---|
| A. Infarctive stroke (final multivariate model: five predictors significant at P < .05) | |||
| Prior TIA | 56.0 | 12.0, 285 | <.001 |
| Steady-state Hb | 1.85 per 1 g/dL* decrease | 1.32, 2.59 | <.001 |
| Acute chest syndrome within 2 weeks prior | 7.03 | 1.85, 26.7 | .001 |
| Acute chest syndrome rate | 2.39 per event/yr | 1.27, 4.48 | .005 |
| Systolic blood pressure | 1.31 per 10 mm Hg increase | 1.03, 1.67 | .033 |
| B. Hemorrhagic stroke (final multivariate model: two predictors significant atP < .05) | |||
| Steady-state Hb | 1.61 per 1 g/dL* decrease | 1.11, 2.35 | .013 |
| Steady-state leukocyte count | 1.94 per 5 × 109/L increase | 1.73, 2.18 | .026 |
Abbreviation: CI, confidence interval.
1 g/dL = 0.6206 mmol/L.