Incidence of First CVA on Study
| Age (yr) . | SS . | SC . | S-β+ . | S-β0 . | Total . |
|---|---|---|---|---|---|
| N | 2,436 | 839 | 188 | 184 | 3,647 |
| <2 | 0.13 (1) | 0.00 | 0.00 | 0.00 | 0.08 (1) |
| 2-5 | 1.02 (20) | 0.27 (2) | 0.00 | 0.00 | 0.75 (22) |
| 6-9 | 0.79 (15) | 0.00 | 0.00 | 0.00 | 0.55 (15) |
| 10-19 | 0.41 (15) | 0.09 (1) | 0.00 | 0.00 | 0.30 (16) |
| 20-29 | 0.52 (14) | 0.16 (1) | 0.46 (1) | 0.43 (1) | 0.45 (17) |
| 30-39 | 0.59 (8) | 0.00 | 0.00 | 0.00 | 0.39 (8) |
| 40-49 | 0.74 (3) | 1.01 (2) | 0.00 | 0.00 | 0.76 (5) |
| ≥50 | 1.28 (2) | 0.76 (1) | 0.00 | 0.00 | 0.91 (3) |
| Overall | 0.61 (78) | 0.17 (7) | 0.11 (1) | 0.10 (1) | 0.46 (87) |
| Age-adjusted | 0.61 | 0.15 | 0.09 | 0.08 |
| Age (yr) . | SS . | SC . | S-β+ . | S-β0 . | Total . |
|---|---|---|---|---|---|
| N | 2,436 | 839 | 188 | 184 | 3,647 |
| <2 | 0.13 (1) | 0.00 | 0.00 | 0.00 | 0.08 (1) |
| 2-5 | 1.02 (20) | 0.27 (2) | 0.00 | 0.00 | 0.75 (22) |
| 6-9 | 0.79 (15) | 0.00 | 0.00 | 0.00 | 0.55 (15) |
| 10-19 | 0.41 (15) | 0.09 (1) | 0.00 | 0.00 | 0.30 (16) |
| 20-29 | 0.52 (14) | 0.16 (1) | 0.46 (1) | 0.43 (1) | 0.45 (17) |
| 30-39 | 0.59 (8) | 0.00 | 0.00 | 0.00 | 0.39 (8) |
| 40-49 | 0.74 (3) | 1.01 (2) | 0.00 | 0.00 | 0.76 (5) |
| ≥50 | 1.28 (2) | 0.76 (1) | 0.00 | 0.00 | 0.91 (3) |
| Overall | 0.61 (78) | 0.17 (7) | 0.11 (1) | 0.10 (1) | 0.46 (87) |
| Age-adjusted | 0.61 | 0.15 | 0.09 | 0.08 |
The number of CVAs per 100 patient-years, by age group at occurrence and hemoglobin genotype, is shown. The number in parentheses represents the number of events.