G-CSF–Mobilized PBPCs Contain Fewer Committed Lymphoid Progenitors Than Bone Marrow
| Source of CD34+ Cells . | % CD34+ Expressing CD7+ . | % CD34+ Expressing CD2+ . | % CD34+ Expressing CD10+ . |
|---|---|---|---|
| Unprimed bone marrow | 3.0 ± 0.3 (22) | 4.8 ± 0.4 (22) | 6.4 ± 1.2 (5) |
| G-CSF–mobilized PBPCs | 0.41 ± 0.11 (8) | 0.09 ± 0.03 (8) | 1.2 ± 0.3 (6) |
| Comparison (BM v PBPCs) | P ≤ .001 | P ≤ .001 | P = .001 |
| Source of CD34+ Cells . | % CD34+ Expressing CD7+ . | % CD34+ Expressing CD2+ . | % CD34+ Expressing CD10+ . |
|---|---|---|---|
| Unprimed bone marrow | 3.0 ± 0.3 (22) | 4.8 ± 0.4 (22) | 6.4 ± 1.2 (5) |
| G-CSF–mobilized PBPCs | 0.41 ± 0.11 (8) | 0.09 ± 0.03 (8) | 1.2 ± 0.3 (6) |
| Comparison (BM v PBPCs) | P ≤ .001 | P ≤ .001 | P = .001 |
CD34+ cells were enriched from each cell source by an avidin-biotin column before phenotyping. The number in parentheses is the number of experiments.