On-Study Clinical Characteristics of 221 PML-RARα–positive INT 0129 Cases as a Function of PML-RARα mRNA Type
| Characteristic or Category* . | PML-RARα mRNA Type . | ||
|---|---|---|---|
| . | S-form . | L-form . | V-form . |
| Age (years) | |||
| 15–55 | 58 (71) | 96 (79) | 16 (89) |
| >55 | 24 (29) | 25 (21) | 2 (11) |
| Sex | |||
| Male | 42 (51) | 73 (61) | 8 (44) |
| Female | 40 (49) | 48 (39) | 10 (56) |
| Race | |||
| White | 61 (74) | 92 (76) | 14 (79) |
| Hispanic | 4 (5) | 10 (8) | 2 (11) |
| Black | 14 (17) | 12 (10) | 1 (5) |
| Other | 3 (4) | 7 (6) | 1 (5) |
| Performance status | |||
| 0–1 | 65 (79) | 102 (84) | 15 (83) |
| >1 | 17 (21) | 19 (16) | 3 (17) |
| Clinical signs of bleeding disorder | |||
| No | 33 (41) | 57 (47) | 5 (28) |
| Yes | 47 (59) | 64 (53) | 12 (71) |
| Characteristic or Category* . | PML-RARα mRNA Type . | ||
|---|---|---|---|
| . | S-form . | L-form . | V-form . |
| Age (years) | |||
| 15–55 | 58 (71) | 96 (79) | 16 (89) |
| >55 | 24 (29) | 25 (21) | 2 (11) |
| Sex | |||
| Male | 42 (51) | 73 (61) | 8 (44) |
| Female | 40 (49) | 48 (39) | 10 (56) |
| Race | |||
| White | 61 (74) | 92 (76) | 14 (79) |
| Hispanic | 4 (5) | 10 (8) | 2 (11) |
| Black | 14 (17) | 12 (10) | 1 (5) |
| Other | 3 (4) | 7 (6) | 1 (5) |
| Performance status | |||
| 0–1 | 65 (79) | 102 (84) | 15 (83) |
| >1 | 17 (21) | 19 (16) | 3 (17) |
| Clinical signs of bleeding disorder | |||
| No | 33 (41) | 57 (47) | 5 (28) |
| Yes | 47 (59) | 64 (53) | 12 (71) |
Results are expressed as the number of cases (percent of cases).
P > .1 for comparisons of S-form versus L-form cases for all characteristics or categories.