Hematologic Parameters and Liver Weights of Leukemic and Nonleukemic Mice
| . | WBC/mL (×10−3) . | Hematocrit (%) . | Platelets/mL (×10−3) . | Nucleated Spleen Cells (×10−6) . | Liver Weight (g) . |
|---|---|---|---|---|---|
| Control nonleukemic (n = 27) | 5.7 ± 1.7 | 45.0 ± 0.9 | 1,348 ± 38 | 359 ± 78 | 1.42 ± 0.05 |
| Control leukemic (n = 19) | 62.2 ± 9.0 | 31.5 ± 1.8 | 572 ± 55 | 1,124 ± 111 | 4.52 ± 0.30 |
| Folate-deficient 1 nonleukemic (n = 16) | 4.0 ± 0.6 | 44.9 ± 0.4 | 1,373 ± 53 | 337 ± 5 | 1.30 ± 0.05 |
| Folate-deficient 1 leukemic (n = 32) | 95.5 ± 16.8 | 31.1 ± 1.7 | 775 ± 86 | 1,369 ± 132 | 4.44 ± 0.26 |
| Folate-deficient 2 nonleukemic (n = 10) | 3.1 ± 0.0 | 45.0 ± 0.6 | 1,458 ± 54 | 228 ± 28 | 1.26 ± 0.05 |
| Folate-deficient 2 leukemic (n = 27) | 82.4 ± 9.7 | 28.0 ± 2.1 | 609 ± 61 | 1,428 ± 173 | 4.50 ± 0.38 |
| . | WBC/mL (×10−3) . | Hematocrit (%) . | Platelets/mL (×10−3) . | Nucleated Spleen Cells (×10−6) . | Liver Weight (g) . |
|---|---|---|---|---|---|
| Control nonleukemic (n = 27) | 5.7 ± 1.7 | 45.0 ± 0.9 | 1,348 ± 38 | 359 ± 78 | 1.42 ± 0.05 |
| Control leukemic (n = 19) | 62.2 ± 9.0 | 31.5 ± 1.8 | 572 ± 55 | 1,124 ± 111 | 4.52 ± 0.30 |
| Folate-deficient 1 nonleukemic (n = 16) | 4.0 ± 0.6 | 44.9 ± 0.4 | 1,373 ± 53 | 337 ± 5 | 1.30 ± 0.05 |
| Folate-deficient 1 leukemic (n = 32) | 95.5 ± 16.8 | 31.1 ± 1.7 | 775 ± 86 | 1,369 ± 132 | 4.44 ± 0.26 |
| Folate-deficient 2 nonleukemic (n = 10) | 3.1 ± 0.0 | 45.0 ± 0.6 | 1,458 ± 54 | 228 ± 28 | 1.26 ± 0.05 |
| Folate-deficient 2 leukemic (n = 27) | 82.4 ± 9.7 | 28.0 ± 2.1 | 609 ± 61 | 1,428 ± 173 | 4.50 ± 0.38 |
Nonleukemic mice are all mice that survived 1 year without developing evidence of leukemia.