Relative Frequency (%) of Complications During Induction Cycle I
| . | Control Group . | GM-CSF . |
|---|---|---|
| . | . | Group . |
| Hemorrhage | ||
| Only petechiae | 21 | 26 |
| Other bleedings | 26 | 25 |
| Liver | ||
| Mild-moderate (1.25-5 × normal) | 31 | 37 |
| Severe (≥5 × normal) | 11 | 10 |
| Oral | ||
| Erythema | 17 | 14 |
| Ulcers and other toxicity | 7 | 12 |
| Nausea/vomiting | 30/35 | 32/34 |
| Diarrhea4-150 | ||
| Less than 2 days | 23 | 23 |
| More severe | 18 | 30 |
| Renal4-150 | ||
| Mild-moderate (1.26-5 × normal) | 21 | 31 |
| Severe (≥5 × normal) | 3 | 3 |
| Fever4-150 | ||
| Subfebrile (<38°C) | 12 | 11 |
| ≥38°C | 71 | 81 |
| Cutaneous4-150 | ||
| Erythema/desquamation/papules etc | 43 | 55 |
| Cardiac rhythm | 22 | 22 |
| Neurotoxicity | 11 | 12 |
| Bone pain | 6 | 8 |
| Hypotension4-151 | 13 | 26 |
| Fluid retention‡ | 56 | 71 |
| Chills‡ | 18 | 37 |
| Phlebitis4-150 | 8 | 17 |
| Infection | 77 | 78 |
| . | Control Group . | GM-CSF . |
|---|---|---|
| . | . | Group . |
| Hemorrhage | ||
| Only petechiae | 21 | 26 |
| Other bleedings | 26 | 25 |
| Liver | ||
| Mild-moderate (1.25-5 × normal) | 31 | 37 |
| Severe (≥5 × normal) | 11 | 10 |
| Oral | ||
| Erythema | 17 | 14 |
| Ulcers and other toxicity | 7 | 12 |
| Nausea/vomiting | 30/35 | 32/34 |
| Diarrhea4-150 | ||
| Less than 2 days | 23 | 23 |
| More severe | 18 | 30 |
| Renal4-150 | ||
| Mild-moderate (1.26-5 × normal) | 21 | 31 |
| Severe (≥5 × normal) | 3 | 3 |
| Fever4-150 | ||
| Subfebrile (<38°C) | 12 | 11 |
| ≥38°C | 71 | 81 |
| Cutaneous4-150 | ||
| Erythema/desquamation/papules etc | 43 | 55 |
| Cardiac rhythm | 22 | 22 |
| Neurotoxicity | 11 | 12 |
| Bone pain | 6 | 8 |
| Hypotension4-151 | 13 | 26 |
| Fluid retention‡ | 56 | 71 |
| Chills‡ | 18 | 37 |
| Phlebitis4-150 | 8 | 17 |
| Infection | 77 | 78 |