Clone-Specific CDRIII DNA Sequences of Representative ALL and NHL Patients
| . | Patient . | VH . | N-DH-N . | JH . |
|---|---|---|---|---|
| 1. | cALL 1267 | |||
| Tumor | CGA | TTCGTTCATTACTATGGTTCGGGGAGTTAAC | CTA | |
| Plasma | CGA | TTCGTTCATTACTATGGTTCGGGGAGTTAAC | CTA | |
| Serum | CGA | TTCGTTCATTACTATGGTTCGGGGAGTTAAC | CTA | |
| 2. | cALL 374 | |||
| Tumor | CGAGAGA | TCGAAGATAGAGAGAGATAGCAGCTCGTCCTAC | TTGACTA | |
| Plasma | CGAGAGA | TCGAAGATAGAGAGAGATAGCAGCTCGTCCTAC | TTGACTA | |
| Serum | CGAGAGA | TCGAAGATAGAGAGAGATAGCAGCTCGTCCTAC | TTGACTA | |
| 3a. | NHL 618 a | |||
| Tumor | CGA | CGCCGCTTATAAGGGAAAAGGATATTGTGGTGGTGACTGCTATATCTGAGGC | GCTTTTGATAT | |
| Plasma | CGA | CGCCGCTTATAAGGGAAAAGGATATTGTGGTGGTGACTGCTATATCTGAGGC | GCTTTTGATAT | |
| Serum | CGA | CGCCGCTTATAAGGGAAAAGGATATTGTGGTGGTGACTGCTATATCTGAGGC | GCTTTTGATAT | |
| 3b. | NHL 618 b | |||
| Tumor | CGAGA | CAAAATAGTGCTTATTACCACGGG | GACTT | |
| Plasma | CGAGA | CAAAATAGTGCTTATTACCACGGG | GACTT | |
| Serum | CGAGA | CAAAATAGTGCTTATTACCACGGG | GACTT | |
| 4. | NHL 1293 | |||
| Tumor | CGAGAG | TAGATGGAAATCGCCGAGGCGTG | GACTA | |
| Plasma | CGAGAG | TAGATGGAAATCGCCGAGGCGTG | GACTA | |
| Serum | CGAGAG | TAGATGGAAATCGCCGAGGCGTG | GACTA | |
| 5. | NHL 833 | |||
| Tumor | CGAGAGA | CTTGGCTGTACCAGCTGGTATGCCCTTTTACAACTCTC | ACTACGGTATGGACGT | |
| Plasma | CGAGAGA | CTTGGCTGTACCAGCTGGTATGCCCTTTTACAACTCTC | ACTACGGTATGGACGT | |
| Serum | CGAGAGA | CTTGGCTGTACCAGCTGGTATGCCCTTTTACAACTCTC | ACTACGGTATGGACGT |
| . | Patient . | VH . | N-DH-N . | JH . |
|---|---|---|---|---|
| 1. | cALL 1267 | |||
| Tumor | CGA | TTCGTTCATTACTATGGTTCGGGGAGTTAAC | CTA | |
| Plasma | CGA | TTCGTTCATTACTATGGTTCGGGGAGTTAAC | CTA | |
| Serum | CGA | TTCGTTCATTACTATGGTTCGGGGAGTTAAC | CTA | |
| 2. | cALL 374 | |||
| Tumor | CGAGAGA | TCGAAGATAGAGAGAGATAGCAGCTCGTCCTAC | TTGACTA | |
| Plasma | CGAGAGA | TCGAAGATAGAGAGAGATAGCAGCTCGTCCTAC | TTGACTA | |
| Serum | CGAGAGA | TCGAAGATAGAGAGAGATAGCAGCTCGTCCTAC | TTGACTA | |
| 3a. | NHL 618 a | |||
| Tumor | CGA | CGCCGCTTATAAGGGAAAAGGATATTGTGGTGGTGACTGCTATATCTGAGGC | GCTTTTGATAT | |
| Plasma | CGA | CGCCGCTTATAAGGGAAAAGGATATTGTGGTGGTGACTGCTATATCTGAGGC | GCTTTTGATAT | |
| Serum | CGA | CGCCGCTTATAAGGGAAAAGGATATTGTGGTGGTGACTGCTATATCTGAGGC | GCTTTTGATAT | |
| 3b. | NHL 618 b | |||
| Tumor | CGAGA | CAAAATAGTGCTTATTACCACGGG | GACTT | |
| Plasma | CGAGA | CAAAATAGTGCTTATTACCACGGG | GACTT | |
| Serum | CGAGA | CAAAATAGTGCTTATTACCACGGG | GACTT | |
| 4. | NHL 1293 | |||
| Tumor | CGAGAG | TAGATGGAAATCGCCGAGGCGTG | GACTA | |
| Plasma | CGAGAG | TAGATGGAAATCGCCGAGGCGTG | GACTA | |
| Serum | CGAGAG | TAGATGGAAATCGCCGAGGCGTG | GACTA | |
| 5. | NHL 833 | |||
| Tumor | CGAGAGA | CTTGGCTGTACCAGCTGGTATGCCCTTTTACAACTCTC | ACTACGGTATGGACGT | |
| Plasma | CGAGAGA | CTTGGCTGTACCAGCTGGTATGCCCTTTTACAACTCTC | ACTACGGTATGGACGT | |
| Serum | CGAGAGA | CTTGGCTGTACCAGCTGGTATGCCCTTTTACAACTCTC | ACTACGGTATGGACGT |
CDRIII sequences in tumor cells, plasma, and serum of patients with NHL and ALL. Patients are identical to those in Fig 1B. In patient no. 618 two clonal rearrangements were shown.