Table 4.

Remission Rate by Age and Cytogenetics

FilgrastimPlaceboTotal
Overall 178/259 (69%) 177/262 (68%) 355/521 (68%) 
Age 
<50 yr 79/104 (76%) 82/115 (71%) 161/219 (74%) 
≥50 yr 99/155 (64%) 95/147 (65%) 194/302 (64%) 
Cytogenetics 
Unfavorable 51/78 (65%) 42/75 (56%) 93/153 (61%) 
Normal/favorable 78/104 (75%) 98/123 (80%) 176/227 (78%) 
Not assessed 49/77 (64%) 37/64 (58%) 86/141 (61%) 
FilgrastimPlaceboTotal
Overall 178/259 (69%) 177/262 (68%) 355/521 (68%) 
Age 
<50 yr 79/104 (76%) 82/115 (71%) 161/219 (74%) 
≥50 yr 99/155 (64%) 95/147 (65%) 194/302 (64%) 
Cytogenetics 
Unfavorable 51/78 (65%) 42/75 (56%) 93/153 (61%) 
Normal/favorable 78/104 (75%) 98/123 (80%) 176/227 (78%) 
Not assessed 49/77 (64%) 37/64 (58%) 86/141 (61%) 

Unfavorable: monosomies 5, 7; trisomy 8; 11q(23); complex and multiple abnormalities. Favorable: t(15; 17), t(8; 21), inv(16).

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