Analysis of CD34+ Marrow Cells in Patients Before DLI and Outcome After DLI
| . | BCR-ABL Neg. in FISH . | Donor Cells in FISH . | Genotype in VNTR-PCR . | Aplasia After DLI . | GVHD After DLI . | Outcome . |
|---|---|---|---|---|---|---|
| . | (%) . | (%) . | . | . | . | . |
| 1a | 90 | NA | Donor | No | Skin:1 | Disease progression |
| 1b | 85 | NA | Donor and recipient | No | Skin:1 Liver:3 | Death in remission |
| 2 | 72 | NA | Recipient | Yes | Skin:2 | Alive in molecular remission for 24 mo |
| Liver:1 | ||||||
| 3 | 45 | 5 | Recipient | Yes | Skin:2 | Death in molecular remission |
| Lung | ||||||
| 4 | 50 | 41 | ND | No | Skin:1 | Alive in molecular remission 5 mo after DLI |
| 5a | NA | 2.4 | Recipient | Yes | Skin:1 | Disease progression |
| 5b | NA | 97 | Donor | No | Skin:1 | Alive in remission 12 mo after DLI |
| 6 | NA | 98 | Donor | No | Skin:1 | Alive in remission 8 mo after DLI |
| 7 | NA | 98 | Donor | No | Skin:1 | Alive in remission 6 mo after DLI |
| . | BCR-ABL Neg. in FISH . | Donor Cells in FISH . | Genotype in VNTR-PCR . | Aplasia After DLI . | GVHD After DLI . | Outcome . |
|---|---|---|---|---|---|---|
| . | (%) . | (%) . | . | . | . | . |
| 1a | 90 | NA | Donor | No | Skin:1 | Disease progression |
| 1b | 85 | NA | Donor and recipient | No | Skin:1 Liver:3 | Death in remission |
| 2 | 72 | NA | Recipient | Yes | Skin:2 | Alive in molecular remission for 24 mo |
| Liver:1 | ||||||
| 3 | 45 | 5 | Recipient | Yes | Skin:2 | Death in molecular remission |
| Lung | ||||||
| 4 | 50 | 41 | ND | No | Skin:1 | Alive in molecular remission 5 mo after DLI |
| 5a | NA | 2.4 | Recipient | Yes | Skin:1 | Disease progression |
| 5b | NA | 97 | Donor | No | Skin:1 | Alive in remission 12 mo after DLI |
| 6 | NA | 98 | Donor | No | Skin:1 | Alive in remission 8 mo after DLI |
| 7 | NA | 98 | Donor | No | Skin:1 | Alive in remission 6 mo after DLI |
Patients 1a and 5a, patients 1 and 5 before first course of DLI. Patients 1b and 5b, patients 1 and 5 before second course of DLI.
Abbreviations: neg, negativity, NA, not applicable; ND, not done.