Table 4. Unrelated Donor Umbilical Cord... | American Society of Hematology

Table 4.

Unrelated Donor Umbilical Cord Blood Transplantation: Review of Reports in the Literature (n = 43)

Median Age	Median Weight	Median Volume	Median Nuc/kg (range) × 10⁷	Median ANC ≥500/μL (range) in Days	Median Platelets ≥50K/μL (range) in Days	Nonmyeloid Engraftment (%)
(range) in yrs	(range) in kg	(range) in mL
4.1	18.7	83.0	3.7	23	75	9%
(0.1-23.5)	(3.3-79.0)	(35-214)	(0.7-40.0)	(14-41)	(67->120*)

Median Age	Median Weight	Median Volume	Median Nuc/kg (range) × 10⁷	Median ANC ≥500/μL (range) in Days	Median Platelets ≥50K/μL (range) in Days	Nonmyeloid Engraftment (%)
(range) in yrs	(range) in kg	(range) in mL
4.1	18.7	83.0	3.7	23	75	9%
(0.1-23.5)	(3.3-79.0)	(35-214)	(0.7-40.0)	(14-41)	(67->120*)

HLA A, B, DRB1 Match^4-151

HLA A, B, DRB1 1-antigen

HLA, A, B, DRB1 2 or 3

All HLA Parity (n = 43) (n = 35)^‡

(n = 8) (n = 6)^‡

(n = 16) (n = 14)^‡

(n = 19) (n = 15)^‡

Grade II-IV aGVHD

Grade III-IV aGVHD

Grade II-IV aGVHD

Grade III-IV aGVHD

Grade II-IV aGVHD

Grade III-IV aGVHD

Grade II-IV aGVHD

Grade III-IV aGVHD

33%

16%

43%

73%

57%

Data are from previous studies.64-66

Some patients did not platelet engraft by day 120.

HLA A, B, DR by serology and DRB1 by high resolution DNA typing.

Evaluable for aGVHD.