Percentage of NOD/SCID Mouse Tissue Cells Expressing Human CD45 Antigen
Patient . | Phenotype . | No. Cells . | Blood4-150 . | Bone . | Spleen4-150 . |
---|---|---|---|---|---|
No. . | . | Injected . | . | Marrow4-150 . | . |
4 | Unsorted | 5 × 106 | 22 | 21 | 3 |
CD34+/Thy-1+ | 6 × 103 | 0 | 0 | 1 | |
CD34+/Thy-1− | 106 | 9 | 25 | 6 | |
CD34− | 106 | 0 | 0 | 0 | |
5 | Unsorted | 5 × 106 | 3 | 0.02 | 0.1 |
CD34+/Thy-1+ | 4 × 104 | 0 | 0 | 0 | |
CD34+/Thy-1− | 5 × 106 | 20 | 3 | 0.2 | |
CD34− | 106 | ND | ND | ND | |
6 | Unsorted | 5 × 106 | 2 | 0.3 | 2 |
Unsorted | 106 | 0.5 | 1 | 0 | |
CD34+/Thy-1+ | 104 | 0 | 0.3 | 0 | |
CD34+/Thy-1− | 106 | 0.3 | 3 | 5 | |
CD34− | 106 | 0 | 0 | 0 | |
7 | Unsorted | 106 | 3.3 | 49 | 7 |
CD34+/Thy-1+ | 2 × 104 | 0.5 | 0.2 | 0 | |
CD34+/Thy-1− | 106 | 5 | 8 | 0 | |
CD34− | 106 | 3 | 0 | 0 | |
8 | Unsorted | 5 × 106 | 3 | 0.3 | 1 |
Unsorted | 106 | 1 | 2 | 0 | |
CD34+/Thy-1+ | 104 | 0 | 0 | 0 | |
CD34+/Thy-1− | 106 | 1 | 0.3 | 3 | |
CD34− | 106 | 0 | 0 | ND | |
9 | Unsorted | 5 × 106 | 89 | 92 | 85 |
Unsorted | 106 | 67 | 55 | 64 | |
CD34+/Thy-1+ | 4 × 102 | 1 | 0.1 | 0 | |
CD34+/Thy-1− | 3 × 104 | 5 | 16 | 2 | |
CD34− | 106 | 0 | 5 | 5 | |
10 | Unsorted | 5 × 106 | 96 | 95 | 94 |
Unsorted | 106 | 44 | 97 | ND | |
CD34+/Thy-1+ | 3 × 103 | 0 | 0 | 0 | |
CD34+/Thy-1− | 104 | 68 | 80 | 72 | |
CD34− | 106 | 84 | 98 | 87 |
Patient . | Phenotype . | No. Cells . | Blood4-150 . | Bone . | Spleen4-150 . |
---|---|---|---|---|---|
No. . | . | Injected . | . | Marrow4-150 . | . |
4 | Unsorted | 5 × 106 | 22 | 21 | 3 |
CD34+/Thy-1+ | 6 × 103 | 0 | 0 | 1 | |
CD34+/Thy-1− | 106 | 9 | 25 | 6 | |
CD34− | 106 | 0 | 0 | 0 | |
5 | Unsorted | 5 × 106 | 3 | 0.02 | 0.1 |
CD34+/Thy-1+ | 4 × 104 | 0 | 0 | 0 | |
CD34+/Thy-1− | 5 × 106 | 20 | 3 | 0.2 | |
CD34− | 106 | ND | ND | ND | |
6 | Unsorted | 5 × 106 | 2 | 0.3 | 2 |
Unsorted | 106 | 0.5 | 1 | 0 | |
CD34+/Thy-1+ | 104 | 0 | 0.3 | 0 | |
CD34+/Thy-1− | 106 | 0.3 | 3 | 5 | |
CD34− | 106 | 0 | 0 | 0 | |
7 | Unsorted | 106 | 3.3 | 49 | 7 |
CD34+/Thy-1+ | 2 × 104 | 0.5 | 0.2 | 0 | |
CD34+/Thy-1− | 106 | 5 | 8 | 0 | |
CD34− | 106 | 3 | 0 | 0 | |
8 | Unsorted | 5 × 106 | 3 | 0.3 | 1 |
Unsorted | 106 | 1 | 2 | 0 | |
CD34+/Thy-1+ | 104 | 0 | 0 | 0 | |
CD34+/Thy-1− | 106 | 1 | 0.3 | 3 | |
CD34− | 106 | 0 | 0 | ND | |
9 | Unsorted | 5 × 106 | 89 | 92 | 85 |
Unsorted | 106 | 67 | 55 | 64 | |
CD34+/Thy-1+ | 4 × 102 | 1 | 0.1 | 0 | |
CD34+/Thy-1− | 3 × 104 | 5 | 16 | 2 | |
CD34− | 106 | 0 | 5 | 5 | |
10 | Unsorted | 5 × 106 | 96 | 95 | 94 |
Unsorted | 106 | 44 | 97 | ND | |
CD34+/Thy-1+ | 3 × 103 | 0 | 0 | 0 | |
CD34+/Thy-1− | 104 | 68 | 80 | 72 | |
CD34− | 106 | 84 | 98 | 87 |
The remainder of cells to 100% were CD45−.