Table 2.

Flow Cytometric Analysis of Multiple Quinine-Dependent Antibodies

MFI
PlateletsT Lymphocytes (CD3+)B Lymphocytes (CD19+)Neutrophils (CD13+)Neutrophils (CD33+)
Normal serum 3.8 ± 2.5 19.3 ± 10.8 3.7 ± 2.2 32.8 ± 15.7 29.2 ± 10.2 
Normal serum + quinine 3.9 ± 2.6 18.2 ± 7.9 3.7 ± 2.2 31.6 ± 14.3 29.9 ± 10.5 
Patient serum 5.8 ± 4.1 18.5 ± 8.2 3.8 ± 2.4 33.9 ± 16.9 30.4 ± 11.4 
Patient serum + quinine 204.7 ± 92.3* 165.6 ± 95* 28.1 ± 13.2* 1159 ± 930* 1300 ± 1011.2* 
MFI
PlateletsT Lymphocytes (CD3+)B Lymphocytes (CD19+)Neutrophils (CD13+)Neutrophils (CD33+)
Normal serum 3.8 ± 2.5 19.3 ± 10.8 3.7 ± 2.2 32.8 ± 15.7 29.2 ± 10.2 
Normal serum + quinine 3.9 ± 2.6 18.2 ± 7.9 3.7 ± 2.2 31.6 ± 14.3 29.9 ± 10.5 
Patient serum 5.8 ± 4.1 18.5 ± 8.2 3.8 ± 2.4 33.9 ± 16.9 30.4 ± 11.4 
Patient serum + quinine 204.7 ± 92.3* 165.6 ± 95* 28.1 ± 13.2* 1159 ± 930* 1300 ± 1011.2* 

The results (mean ± SD of 6 experiments) are expressed as median fluorescence intensity (MFI).

*

P < .01. Comparisons were made for patient serum in the presence and absence of quinine.

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