Hematology Profile of IL11Ra−/− Mice
| . | Genotype* . | |
|---|---|---|
| . | +/+ . | −/− . |
| Peripheral blood | ||
| Platelets (×106/mL) | 904 ± 86 | 901 ± 87 |
| Hematocrit (%) | 47 ± 3.5 | 47 ± 2.8 |
| White blood cell count (×106/mL) | 6.9 ± 3.1 | 5.5 ± 1.9 |
| Neutrophils | 0.5 ± 0.2 | 0.38 ± 0.31 |
| Lymphocytes | 4.2 ± 0.9 | 4.4 ± 1.3 |
| Monocytes | 0.42 ± 0.13 | 0.40 ± 0.15 |
| Eosinophils | 0.08 ± 0.06 | 0.05 ± 0.03 |
| Red blood cell reticulocytes (%) | 3 ± 2 | 2 ± 1 |
| Bone marrow | ||
| Cellularity (×106/femur) | 10.7 ± 2.7 | 13.0 ± 2.9 |
| Blasts (%) | 2 ± 1 | 2 ± 1 |
| Promyelocytes/myelocytes (%) | 5 ± 1 | 4 ± 1 |
| Metamyelocytes/neutrophils (%) | 26 ± 7 | 26 ± 6 |
| Lymphocytes (%) | 29 ± 7 | 30 ± 6 |
| Monocytes | 6 ± 1 | 5 ± 2 |
| Eosinophils (%) | 3 ± 1 | 4 ± 2 |
| Nucleated erythroid cells (%) | 30 ± 11 | 27 ± 9 |
| Megakaryocytes (per 20 hpf)† | 130 ± 19 | 121 ± 24 |
| Spleen | ||
| Weight (mg) | 90 ± 10 | 89 ± 11 |
| Cellularity (×106) | 121 ± 78 | 138 ± 104 |
| Blasts (%) | 1 ± 1 | 1 ± 1 |
| Promyelocytes/myelocytes (%) | 2 ± 1 | 1 ± 1 |
| Metamyelocytes/neutrophils (%) | 2 ± 1 | 3 ± 2 |
| Lymphocytes (%) | 80 ± 8 | 78 ± 10 |
| Monocytes | 8 ± 3 | 6 ± 4 |
| Eosinophils (%) | 1 ± 1 | 1 ± 1 |
| Nucleated erythroid cells (%) | 6 ± 7 | 10 ± 11 |
| Megakaryocytes (per 20 hpf)† | 11 ± 4 | 18 ± 7 |
| . | Genotype* . | |
|---|---|---|
| . | +/+ . | −/− . |
| Peripheral blood | ||
| Platelets (×106/mL) | 904 ± 86 | 901 ± 87 |
| Hematocrit (%) | 47 ± 3.5 | 47 ± 2.8 |
| White blood cell count (×106/mL) | 6.9 ± 3.1 | 5.5 ± 1.9 |
| Neutrophils | 0.5 ± 0.2 | 0.38 ± 0.31 |
| Lymphocytes | 4.2 ± 0.9 | 4.4 ± 1.3 |
| Monocytes | 0.42 ± 0.13 | 0.40 ± 0.15 |
| Eosinophils | 0.08 ± 0.06 | 0.05 ± 0.03 |
| Red blood cell reticulocytes (%) | 3 ± 2 | 2 ± 1 |
| Bone marrow | ||
| Cellularity (×106/femur) | 10.7 ± 2.7 | 13.0 ± 2.9 |
| Blasts (%) | 2 ± 1 | 2 ± 1 |
| Promyelocytes/myelocytes (%) | 5 ± 1 | 4 ± 1 |
| Metamyelocytes/neutrophils (%) | 26 ± 7 | 26 ± 6 |
| Lymphocytes (%) | 29 ± 7 | 30 ± 6 |
| Monocytes | 6 ± 1 | 5 ± 2 |
| Eosinophils (%) | 3 ± 1 | 4 ± 2 |
| Nucleated erythroid cells (%) | 30 ± 11 | 27 ± 9 |
| Megakaryocytes (per 20 hpf)† | 130 ± 19 | 121 ± 24 |
| Spleen | ||
| Weight (mg) | 90 ± 10 | 89 ± 11 |
| Cellularity (×106) | 121 ± 78 | 138 ± 104 |
| Blasts (%) | 1 ± 1 | 1 ± 1 |
| Promyelocytes/myelocytes (%) | 2 ± 1 | 1 ± 1 |
| Metamyelocytes/neutrophils (%) | 2 ± 1 | 3 ± 2 |
| Lymphocytes (%) | 80 ± 8 | 78 ± 10 |
| Monocytes | 8 ± 3 | 6 ± 4 |
| Eosinophils (%) | 1 ± 1 | 1 ± 1 |
| Nucleated erythroid cells (%) | 6 ± 7 | 10 ± 11 |
| Megakaryocytes (per 20 hpf)† | 11 ± 4 | 18 ± 7 |