Binding constants derived from the data shown in Figs 5 and 6 are shown. Because of the functional nature of the binding assay, B_max is equivalent to the maximum rate of plasmin generation by tPA (or K2P) bound to that site. By comparison, uPA binding to uPAR on these cells gives a maximum plasmin generation rate of 24 (±4) pmol/L⋅min⁻¹ in the absence of 6AHA.

Abbreviation: ND, not detected.

Because the binding has not been formally shown to reach equilibrium under these experimental conditions, the parameter determined is not a true equilibrium constant and is thus referred to as an apparent kd.

Expressed as pmol/L⋅min⁻¹.