Table 1.

Patient Characteristics

LPC GroupHPC GroupP Value
(BPC <1%)(BPC ≥1%)
No. (%)No. (%)
(n = 31)(n = 20)
Mean age (range) 69 (42-87) 71 (51-91) NS* 
M-component type  14 (70%) NS 
IgG type 22 (71%) 
Other 9 (29%) 6 (30%) 
ECOG   P < .01 
0-2 22 (71%) 5 (25%) 
3-4 9 (29%) 15 (75%) 
Stage   P < .01 
I or II 18 (58%) 4 (20%) 
III 13 (41%) 16 (80%) 
Lytic bone lesions   NS 
≤3 or osteoporosis 22 (71%) 14 (70%) 
>3 9 (29%) 6 (30%) 
Creatinin (mg/dL) 1.13 (0.6-6.4) 1.55 (0.6-7.1) NS* 
CD56 13 (42%) 8 (40%) NS 
CD56+ 18 (58%) 12 (60%) 
% Infiltration 31.07 ± 17.35 53.44 ± 22.45 P < .01* 
Ki67 2.16 ± 2.7 6.53 ± 5.27 P < .01* 
β2 microglobulin 4.34 ± 2.85 8.88 ± 8.66 P < .01* 
Response 14/21 (67%) 2/17 (12%) P < .05 
LPC GroupHPC GroupP Value
(BPC <1%)(BPC ≥1%)
No. (%)No. (%)
(n = 31)(n = 20)
Mean age (range) 69 (42-87) 71 (51-91) NS* 
M-component type  14 (70%) NS 
IgG type 22 (71%) 
Other 9 (29%) 6 (30%) 
ECOG   P < .01 
0-2 22 (71%) 5 (25%) 
3-4 9 (29%) 15 (75%) 
Stage   P < .01 
I or II 18 (58%) 4 (20%) 
III 13 (41%) 16 (80%) 
Lytic bone lesions   NS 
≤3 or osteoporosis 22 (71%) 14 (70%) 
>3 9 (29%) 6 (30%) 
Creatinin (mg/dL) 1.13 (0.6-6.4) 1.55 (0.6-7.1) NS* 
CD56 13 (42%) 8 (40%) NS 
CD56+ 18 (58%) 12 (60%) 
% Infiltration 31.07 ± 17.35 53.44 ± 22.45 P < .01* 
Ki67 2.16 ± 2.7 6.53 ± 5.27 P < .01* 
β2 microglobulin 4.34 ± 2.85 8.88 ± 8.66 P < .01* 
Response 14/21 (67%) 2/17 (12%) P < .05 

Comparisons between groups were made by the non-parametric Mann-Whitney test (*) for quantitative variables and the χ2 test for qualitative variables (†).

Abbreviation: NS, nonsignificance (P value >.05).

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