Table 3.

Binding Interactions in the Core of HS3

HS3 DNase I Footprint22 23 Factors Bound18 23 Corresponding PhylogeneticFactors Bound to Phylogenetic
FootprintFootprint Probes
Footprint 1 GATA-1 FP6 GATA-1 
 Factor X  CSBP-2 
Footprint 2 Sp1 Not conserved ND 
 TEF-2   
 4 unidentified proteins   
Footprint 3 GATA-1 FP7 GATA-1 
Footprint 4 Sp1 FP8, FP9, FP10, FP11 (partial) Sp1 
 CACCC binding protein  SSP 
 7 unidentified proteins  G1/G2 
   CSBP-2 
   YY1 (two sites) 
Footprint 5 GATA-1 FP9 (partial) GATA-1 
  FP10 (partial), FP11 YY1 
   CSBP-2 
Footprint 6 Sp1 Not conserved ND 
 4 unidentified proteins   
HS3 DNase I Footprint22 23 Factors Bound18 23 Corresponding PhylogeneticFactors Bound to Phylogenetic
FootprintFootprint Probes
Footprint 1 GATA-1 FP6 GATA-1 
 Factor X  CSBP-2 
Footprint 2 Sp1 Not conserved ND 
 TEF-2   
 4 unidentified proteins   
Footprint 3 GATA-1 FP7 GATA-1 
Footprint 4 Sp1 FP8, FP9, FP10, FP11 (partial) Sp1 
 CACCC binding protein  SSP 
 7 unidentified proteins  G1/G2 
   CSBP-2 
   YY1 (two sites) 
Footprint 5 GATA-1 FP9 (partial) GATA-1 
  FP10 (partial), FP11 YY1 
   CSBP-2 
Footprint 6 Sp1 Not conserved ND 
 4 unidentified proteins   

Abbreviation: ND, not determined.

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