Clinical Characteristics of Patients Showing Different HTLV-I Integration Patterns During the Course of the Disease
| Patient No. . | Age/Sex . | Date . | Symptom . | PS . | TIL . | Organ Involvement . | Clinical Subtype . | Morphology of Abnormal Lymphocytes . | Response to Chemotherapy . | Survival . |
|---|---|---|---|---|---|---|---|---|---|---|
| . | . | . | . | . | . | . | . | . | . | (mo) . |
| 1 | 58/M | 1987.12 | Lymphadenopathy | 1 | 3 | PB, LN, liver | Acute | Mature bilobulated | PR | |
| 1989.7 | Paraplegia | 4 | 2 | PB, bone | Acute | Mature bilobulated | PD | 14 | ||
| 2 | 56/M | 1989.1 | None | 0 | 1 | PB | Chronic | Mature bilobulated | ||
| 1991.6 | Eruption | 1 | 2 | PB, skin | Chronic | Mature bilobulated | ||||
| 1992.10 | Malaise | 2 | 4 | PB, skin, LN | Acute | Mature bilobulated | PD | 2 | ||
| 3 | 63/F | 1989.3 | None | 0 | 1 | PB | Chronic | Mature bilobulated | ||
| 1995.4 | Lymphadenopathy | 0 | 2 | PB, LN | Acute | Mature bilobulated | PR | 8† | ||
| 1995.7 | None | 0 | 1 | PB | Acute | Mature bilobulated | ||||
| 4 | 46/F | 1991.2 | Eruption | 0 | 2 | PB, skin | Smoldering | Mature bilobulated | ||
| 1991.12 | Eruption | 1 | 2 | PB, skin | Smoldering | Mature bilobulated | PR* | |||
| 1993.11 | Abdominal fullness | 4 | 5 | PB, BM, liver meninx | Acute | Blastic convoluted | PD | 2 |
| Patient No. . | Age/Sex . | Date . | Symptom . | PS . | TIL . | Organ Involvement . | Clinical Subtype . | Morphology of Abnormal Lymphocytes . | Response to Chemotherapy . | Survival . |
|---|---|---|---|---|---|---|---|---|---|---|
| . | . | . | . | . | . | . | . | . | . | (mo) . |
| 1 | 58/M | 1987.12 | Lymphadenopathy | 1 | 3 | PB, LN, liver | Acute | Mature bilobulated | PR | |
| 1989.7 | Paraplegia | 4 | 2 | PB, bone | Acute | Mature bilobulated | PD | 14 | ||
| 2 | 56/M | 1989.1 | None | 0 | 1 | PB | Chronic | Mature bilobulated | ||
| 1991.6 | Eruption | 1 | 2 | PB, skin | Chronic | Mature bilobulated | ||||
| 1992.10 | Malaise | 2 | 4 | PB, skin, LN | Acute | Mature bilobulated | PD | 2 | ||
| 3 | 63/F | 1989.3 | None | 0 | 1 | PB | Chronic | Mature bilobulated | ||
| 1995.4 | Lymphadenopathy | 0 | 2 | PB, LN | Acute | Mature bilobulated | PR | 8† | ||
| 1995.7 | None | 0 | 1 | PB | Acute | Mature bilobulated | ||||
| 4 | 46/F | 1991.2 | Eruption | 0 | 2 | PB, skin | Smoldering | Mature bilobulated | ||
| 1991.12 | Eruption | 1 | 2 | PB, skin | Smoldering | Mature bilobulated | PR* | |||
| 1993.11 | Abdominal fullness | 4 | 5 | PB, BM, liver meninx | Acute | Blastic convoluted | PD | 2 |
Abbreviations: PB, peripheral blood; LN lymphnode; PR, partial remission; PD, progressive disease.
Mild combination chemotherapy for erythroderma.