Expression of the TGF-β Type II Receptor and Production of TGF-β
. | TGF-β Type II Receptor* (fold change in MFI) . | . | TGF-β Production* (pg/mL) . | ||
---|---|---|---|---|---|
. | . | . | . | Total . | Active . |
CLL B cells (mean ± SD) | (n = 12) | 1.75 ± .61 | (n = 17) | 233 ± 118 | 42 ± 98 |
Normal B cells (mean ± SD) | (n = 7) | 2.06 ± 1.06 | (n = 9) | 186 ± 98 | 8 ± 11 |
. | TGF-β Type II Receptor* (fold change in MFI) . | . | TGF-β Production* (pg/mL) . | ||
---|---|---|---|---|---|
. | . | . | . | Total . | Active . |
CLL B cells (mean ± SD) | (n = 12) | 1.75 ± .61 | (n = 17) | 233 ± 118 | 42 ± 98 |
Normal B cells (mean ± SD) | (n = 7) | 2.06 ± 1.06 | (n = 9) | 186 ± 98 | 8 ± 11 |
Cells or supernatants were obtained after 48 hours in culture; not significantly different, P > .05 as determined by Student's t-test.