Effect of TBI Dose on Engraftment of TCD B6129 BM
| Group . | No. of Mice . | Dose of TBI (cGy) . | (%) Donor T Cells in Spleen . |
|---|---|---|---|
| I | 4 | 700 | 1, 2, 1, 1 |
| II | 4 | 800 | 1, 1, 1, 1 |
| III | 4 | 900 | 4, 70, 1, 59 |
| IV | 4 | 1,000 | 74, 68, 66, 72 |
| Group . | No. of Mice . | Dose of TBI (cGy) . | (%) Donor T Cells in Spleen . |
|---|---|---|---|
| I | 4 | 700 | 1, 2, 1, 1 |
| II | 4 | 800 | 1, 1, 1, 1 |
| III | 4 | 900 | 4, 70, 1, 59 |
| IV | 4 | 1,000 | 74, 68, 66, 72 |
AKR recipients were irradiated with increasing exposures of TBI and then transplanted with 10 × 106 TCD B6129 BM. Animals were sacrificed 45 to 62 days posttransplant and T-cell chimerism in the spleen was assessed. Donor T cells were defined as Thy 1.2+/L3T4+ and Thy 1.2+/Lyt2+.