Hematologic Changes After the Initial Anti-D Treatment: Evaluation of Clinical Variables
| Significant Positive Effect . | Trend . | No Significant Effect . |
|---|---|---|
| PLATELET INCREASE | ||
| Blood type Rh+ 8-150 | Dose of anti-D | Gender |
| Duration of ITP | ||
| Prescence of spleen | HIV infection (adults) | |
| Baseline hemoglobin ≥12 g/dL (adults) | Pretreatment platelet count | |
| Age <20 yr | Solvent detergent treatment | |
| HIV− (children) | Administration (heavy or light) | |
| Hemoglobin decrease after treatment | ||
| RESPONSE DURATION | ||
| Peak platelet increase | Age | |
| HIV infection | ||
| HEMOGLOBIN DECREASE No variables with significant effect or trend were identified | ||
| Significant Positive Effect . | Trend . | No Significant Effect . |
|---|---|---|
| PLATELET INCREASE | ||
| Blood type Rh+ 8-150 | Dose of anti-D | Gender |
| Duration of ITP | ||
| Prescence of spleen | HIV infection (adults) | |
| Baseline hemoglobin ≥12 g/dL (adults) | Pretreatment platelet count | |
| Age <20 yr | Solvent detergent treatment | |
| HIV− (children) | Administration (heavy or light) | |
| Hemoglobin decrease after treatment | ||
| RESPONSE DURATION | ||
| Peak platelet increase | Age | |
| HIV infection | ||
| HEMOGLOBIN DECREASE No variables with significant effect or trend were identified | ||
The level of significance was set at .05.
Not evaluated in this study (see Oksenhendler et al33 and Bussel et al34 ).