Response to Initial Anti-D Treatment: Platelet Increase and Hemoglobin Decrease
| . | All Patients . | Age . | Gender . | Disease Duration . | HIV Status . | ||||
|---|---|---|---|---|---|---|---|---|---|
| . | . | <18 yr . | >18 yr . | Male . | Female . | Acute . | Chronic . | HIV− . | HIV+ . |
| Patients (N) | (261) | (124) | (137) | (152) | (109) | (75) | (186) | (156) | (105) |
| Mean platelet increase (×1,000/μL) | 76 | 110 | 45 | 72 | 84 | 82 | 74 | 95 | 49 |
| SD | 97.3 | 122.9 | 49.5 | 83.0 | 114.4 | 117.3 | 88.3 | 114.3 | 54.0 |
| Response rate (%) | 72 | 81 | 65 | 71 | 74 | 73 | 72 | 78 | 64 |
| Patients (N) | (253) | (119) | (134) | (149) | (104) | (73) | (180) | (150) | (103) |
| Mean hemoglobin decrease (g/dL) | 0.8 | 0.9 | 0.8 | 0.7 | 1.0 | 0.7 | 0.9 | 0.9 | 0.7 |
| SD | 1.1 | 1.1 | 1.1 | 1.2 | 1.0 | 1.0 | 1.2 | 1.1 | 1.2 |
| P value (platelet increase) | P < .001 | P = NS | P = NS | P < .001 | |||||
| . | All Patients . | Age . | Gender . | Disease Duration . | HIV Status . | ||||
|---|---|---|---|---|---|---|---|---|---|
| . | . | <18 yr . | >18 yr . | Male . | Female . | Acute . | Chronic . | HIV− . | HIV+ . |
| Patients (N) | (261) | (124) | (137) | (152) | (109) | (75) | (186) | (156) | (105) |
| Mean platelet increase (×1,000/μL) | 76 | 110 | 45 | 72 | 84 | 82 | 74 | 95 | 49 |
| SD | 97.3 | 122.9 | 49.5 | 83.0 | 114.4 | 117.3 | 88.3 | 114.3 | 54.0 |
| Response rate (%) | 72 | 81 | 65 | 71 | 74 | 73 | 72 | 78 | 64 |
| Patients (N) | (253) | (119) | (134) | (149) | (104) | (73) | (180) | (150) | (103) |
| Mean hemoglobin decrease (g/dL) | 0.8 | 0.9 | 0.8 | 0.7 | 1.0 | 0.7 | 0.9 | 0.9 | 0.7 |
| SD | 1.1 | 1.1 | 1.1 | 1.2 | 1.0 | 1.0 | 1.2 | 1.1 | 1.2 |
| P value (platelet increase) | P < .001 | P = NS | P = NS | P < .001 | |||||
Platelet increase and hemoglobin decrease were calculated as the difference between the pretreatment and the day 7 posttreatment value. Response was defined as a platelet increase ≥20.