Table 1.

Tested Range and Median Concentration of LD70 of Each Drug

Abbreviation (drug name)Tested Range (μg/mL) Maximum-MinimumMedian
Concentration (μg/mL) of LD70
DNR (daunorubicin)  0.8-0.00128 0.087 
ACR (aclarubicin)  0.8-0.00128 0.08 
VP16 (etoposide) 20-0.032 1.05 
L-ASP (L-asparaginase) 10-0.016* 1.925* 
THP-ADR (pirarubicin)  0.8-0.00128 0.135 
MIT (mitoxantrone)  0.4-0.00064 0.08 
L-PAM (melphalan) 20-0.032 5.75 
4HC (4-hydroperoxy-CPA) 40-0.064 5.2 
AraC (cytarabine) 40-0.064 
MTX (methotrexate) 500-0.8 500 
BLM (bleomycine) 40-0.064 40 
VCR (vincristine) 1-0.0016 
VLB (vinblastine) 10-0.016 2.8 
MMC (mitomycin C) 2-0.0032 0.3 
Pred (prednisolone) 100-0.16 36 
Dex (dexamethasone) 4-0.0064 35 
Abbreviation (drug name)Tested Range (μg/mL) Maximum-MinimumMedian
Concentration (μg/mL) of LD70
DNR (daunorubicin)  0.8-0.00128 0.087 
ACR (aclarubicin)  0.8-0.00128 0.08 
VP16 (etoposide) 20-0.032 1.05 
L-ASP (L-asparaginase) 10-0.016* 1.925* 
THP-ADR (pirarubicin)  0.8-0.00128 0.135 
MIT (mitoxantrone)  0.4-0.00064 0.08 
L-PAM (melphalan) 20-0.032 5.75 
4HC (4-hydroperoxy-CPA) 40-0.064 5.2 
AraC (cytarabine) 40-0.064 
MTX (methotrexate) 500-0.8 500 
BLM (bleomycine) 40-0.064 40 
VCR (vincristine) 1-0.0016 
VLB (vinblastine) 10-0.016 2.8 
MMC (mitomycin C) 2-0.0032 0.3 
Pred (prednisolone) 100-0.16 36 
Dex (dexamethasone) 4-0.0064 35 
*

Values are units per milliliter.

Cyclophosphamide.

Percentage of leukemic cell survival.

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