Table 4.

Cox Regression Analysis: Conventional Salvage Therapy Patients

OSEFS
PP
All variables 
Response to salvage therapy <.01 <.01 
Months of prior MOP(P) chemotherapy .05 NS 
Duration of remission NS <.01 
Age at relapse .02 NS 
B symptoms at relapse .12 NS 
Percentage of optimal chemotherapy at relapse .04 .02 
Radiation therapy only at relapse <.01 .05 
Stage of disease at relapse .03 NS 
 
Excluding response 
Months of prior MOP(P) chemotherapy .02 .16 
Duration of remission .07 <.01 
Age at relapse .15 NS 
B symptoms at relapse .01 NS 
Percentage of optimal chemotherapy at relapse .05 <.01 
Radiation therapy only at relapse .17 .02 
OSEFS
PP
All variables 
Response to salvage therapy <.01 <.01 
Months of prior MOP(P) chemotherapy .05 NS 
Duration of remission NS <.01 
Age at relapse .02 NS 
B symptoms at relapse .12 NS 
Percentage of optimal chemotherapy at relapse .04 .02 
Radiation therapy only at relapse <.01 .05 
Stage of disease at relapse .03 NS 
 
Excluding response 
Months of prior MOP(P) chemotherapy .02 .16 
Duration of remission .07 <.01 
Age at relapse .15 NS 
B symptoms at relapse .01 NS 
Percentage of optimal chemotherapy at relapse .05 <.01 
Radiation therapy only at relapse .17 .02 

Other variables entered into the analysis include: stage at initial diagnosis, B symptoms at initial diagnosis, initial treatment with radiotherapy alone, stage at relapse, number of extra nodal disease sites at relapse, reinduction with the initial chemotherapy regimen, prior radiotherapy, relapse in site of prior radiotherapy.

Abbreviations: OS, overall survival; EFS, event-free survival; not significant (NS): P > .20.

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