Table 1. Effect of Anti-Fas MoAb... | American Society of Hematology

Table 1.

Effect of Anti-Fas MoAb Treatment on Apoptosis of Neutrophils From Normal Donors and CGD Patients

Source	Additive	Amount of Additive (ng/mL)	Apoptosis (%) After Culture for
			12 h	24 h
Normal	None		32.5 ± 6.8	62.3 ± 12.4
	Control IgM	300	34.2 ± 7.3	64.9 ± 10.7
	Anti-Fas	10	37.5 ± 6.2	ND
	Anti-Fas	100	66.7 ± 4.0	89.5 ± 4.2
	Anti-Fas	300	85.7 ± 5.1	91.5 ± 3.4
CGD	None		6.1 ± 1.5^*	10.5 ± 4.1^†
	Control IgM	300	7.4 ± 1.8^*	11.7 ± 4.9^†
	Anti-Fas	10	6.9 ± 2.3^†	ND
	Anti-Fas	30	13.8 ± 3.6^†	ND
	Anti-Fas	100	16.5 ± 2.9^†	26.2 ± 6.1^†
	Anti-Fas	300	21.4 ± 3.8^†	35.7 ± 8.4^†

Source	Additive	Amount of Additive (ng/mL)	Apoptosis (%) After Culture for
			12 h	24 h
Normal	None		32.5 ± 6.8	62.3 ± 12.4
	Control IgM	300	34.2 ± 7.3	64.9 ± 10.7
	Anti-Fas	10	37.5 ± 6.2	ND
	Anti-Fas	100	66.7 ± 4.0	89.5 ± 4.2
	Anti-Fas	300	85.7 ± 5.1	91.5 ± 3.4
CGD	None		6.1 ± 1.5^*	10.5 ± 4.1^†
	Control IgM	300	7.4 ± 1.8^*	11.7 ± 4.9^†
	Anti-Fas	10	6.9 ± 2.3^†	ND
	Anti-Fas	30	13.8 ± 3.6^†	ND
	Anti-Fas	100	16.5 ± 2.9^†	26.2 ± 6.1^†
	Anti-Fas	300	21.4 ± 3.8^†	35.7 ± 8.4^†

Data are expressed as mean percentages ± SD from 4 different experiments.

Abbreviation: ND, not done.

P < .05.

P < .01 versus normal neutrophils.