Karyotypes of the 21 Myeloid Leukemias
| Tumor . | Karyotype . |
|---|---|
| CML | |
| 1 | 46,XX,t(9; 22)(q34;q11)[8]/46,XX,del(7)(q11.2q22),t(9; 22)(q34;q11)[7] |
| 2 | 46,XY,t(9; 22)(q34;q11)[7]/46,XX,del(7)(q22q22),t(9; 22)(q34;q11)[3] |
| MDS | |
| 3 | 46,XY[7]/46,XY,del(7)(q22)[3] |
| 4 | 46,XX[3]/46,XX,add(6)(p21),del(7)(q22q36)[7] |
| 5 | 46,XX,del(7)(q22)[10] |
| 6* | 46,XY,t(3; 7)(p13;q22)[20] |
| De novo AML | |
| 7 | 47,XY,del(7)(q22q36),+8[20] |
| 8 | 46,XY,del(7)(q11q36),?t(8; 19)(q24;q11),del(9)(q11q22), add(21)(p11)[5]/46,XY[15] |
| 9 | 48,XY,del(3)(p21),+4,der(5)t(5; 13)(q31;q12 or 14),del(7)(q22),−13,+22,+mar[20] |
| 10 | 46,XY,del(7)(q22q32)[15] |
| 11 | 50,XY,der(5)t(1; 5)(p22;q13),del(7)(q22),+11,−13, add(16)(q2?),−21,+5mar[12] |
| 12 | 47,XY,−5,del(7)(q21),+8,+r(11q?),−13,add(17)(p11), +mar[15] |
| 13 | 45,XY,add(2)(q3?),del(3)(q21),−5,del(7)(q2?1),der(13; 21)(q10;q10),−17,add(21)(p11),+r,inc[6] |
| 14 | 46,XX,t(2; 11)(q37;q23),del(7)(q11)[21] |
| 15 | 45,Y,del(X)(p11),−2,add(3)(q2?7),add(3)(p21),del(4) (q21q31),−5,del(7)(q22q32),add(8)(q2?4),del(9) (p22),−13,add(16)(p13),der(17)t(2; 17)(q21;p11), +mar1,+mar2[16] |
| 16 | 49,XY,del(7)(q22),+8,t(8; 16)(p11;p13),+13,+13[15] |
| 17† | No evaluable metaphases |
| 18 | 46,XX,+del(1)(p22),del(7)(q11q32 or 34),−13[15] |
| 19 | 46,XX[7]/46,XX,t(3; 7)(q28;q22)[22] |
| t-AML | |
| 20 | 40,XY,−5,−6,add(7)(q?),−9,add(12)(p11or13),+13, −14,−15,−16,−16,der(?)t(?; 17)(?;q21),−20,−22, +mar1,+mar2,inc[5] |
| 21 | 46,XX,del(3)(q21q27),add(7)(q22),add(19)(p13)[15] |
| Tumor . | Karyotype . |
|---|---|
| CML | |
| 1 | 46,XX,t(9; 22)(q34;q11)[8]/46,XX,del(7)(q11.2q22),t(9; 22)(q34;q11)[7] |
| 2 | 46,XY,t(9; 22)(q34;q11)[7]/46,XX,del(7)(q22q22),t(9; 22)(q34;q11)[3] |
| MDS | |
| 3 | 46,XY[7]/46,XY,del(7)(q22)[3] |
| 4 | 46,XX[3]/46,XX,add(6)(p21),del(7)(q22q36)[7] |
| 5 | 46,XX,del(7)(q22)[10] |
| 6* | 46,XY,t(3; 7)(p13;q22)[20] |
| De novo AML | |
| 7 | 47,XY,del(7)(q22q36),+8[20] |
| 8 | 46,XY,del(7)(q11q36),?t(8; 19)(q24;q11),del(9)(q11q22), add(21)(p11)[5]/46,XY[15] |
| 9 | 48,XY,del(3)(p21),+4,der(5)t(5; 13)(q31;q12 or 14),del(7)(q22),−13,+22,+mar[20] |
| 10 | 46,XY,del(7)(q22q32)[15] |
| 11 | 50,XY,der(5)t(1; 5)(p22;q13),del(7)(q22),+11,−13, add(16)(q2?),−21,+5mar[12] |
| 12 | 47,XY,−5,del(7)(q21),+8,+r(11q?),−13,add(17)(p11), +mar[15] |
| 13 | 45,XY,add(2)(q3?),del(3)(q21),−5,del(7)(q2?1),der(13; 21)(q10;q10),−17,add(21)(p11),+r,inc[6] |
| 14 | 46,XX,t(2; 11)(q37;q23),del(7)(q11)[21] |
| 15 | 45,Y,del(X)(p11),−2,add(3)(q2?7),add(3)(p21),del(4) (q21q31),−5,del(7)(q22q32),add(8)(q2?4),del(9) (p22),−13,add(16)(p13),der(17)t(2; 17)(q21;p11), +mar1,+mar2[16] |
| 16 | 49,XY,del(7)(q22),+8,t(8; 16)(p11;p13),+13,+13[15] |
| 17† | No evaluable metaphases |
| 18 | 46,XX,+del(1)(p22),del(7)(q11q32 or 34),−13[15] |
| 19 | 46,XX[7]/46,XX,t(3; 7)(q28;q22)[22] |
| t-AML | |
| 20 | 40,XY,−5,−6,add(7)(q?),−9,add(12)(p11or13),+13, −14,−15,−16,−16,der(?)t(?; 17)(?;q21),−20,−22, +mar1,+mar2,inc[5] |
| 21 | 46,XX,del(3)(q21q27),add(7)(q22),add(19)(p13)[15] |