Table 1.

Clinical and Laboratory Characteristics of Cholecystectomy Patients

Group 1 (Randomized Aggressive Tx) % (N = 110)Group 2 (Randomized Conservative Tx) % (N = 120)Group 3 (Nontransfusion) % (N = 37)Group 4 (Nonrandomized Transfusion) % (N = 97)Total %
(N = 364)
Sex 
Male 57  56  38  52  53  
Female 43  44  62  48  47  
Age (yr) 
0-9 24  23  0  25  21  
10-19 52  51  16  51  48  
20+ 25  26  84*  25  31  
Mean age 16.2 16.5 28.0* 16.5 17.6 
ASA physical status 
ASA 2 50  49  62  44  49  
ASA 3 48  50  38  55  49  
ASA 4 2  1  0  1  1  
Past medical history 
Pulmonary disease 35  30  38  33  33  
Asthma 5  5  3  3  4  
Smoking history 9  7  19  8  9  
Cardiac disease 5  4  11  8  6  
Renal disease 0  3  8  5  3  
CNS disease 7  3  3  14  7  
No. hospitalizations in past year 
None 27  20  24  18  22  
1-4 64  68  57  67  65  
5+ 8  13  19  15  13  
Average days hospitalized 7.1 8.4 8.9 9.7 8.4 
Transfusion history 
No prior transfusions 22  25  22  18  22  
<= 10 prior transfusions 54  53  57  56  54  
> 10 prior transfusions 24  23  22  26  24  
Alloimmunized 19  10  19  11  14  
Previous transfusion reactions 5  4  5  8  6  
Preoperative screening labs 
Preoperative hypoxia 3  6  4  2  4  
Abnormal CXR 12  7  10  18  11  
Abnormal SGPT (>60 U/L) 16  17  21  31  21  
Creatinine > 1.5 mg/dL 4  5  3  2  4  
Group 1 (Randomized Aggressive Tx) % (N = 110)Group 2 (Randomized Conservative Tx) % (N = 120)Group 3 (Nontransfusion) % (N = 37)Group 4 (Nonrandomized Transfusion) % (N = 97)Total %
(N = 364)
Sex 
Male 57  56  38  52  53  
Female 43  44  62  48  47  
Age (yr) 
0-9 24  23  0  25  21  
10-19 52  51  16  51  48  
20+ 25  26  84*  25  31  
Mean age 16.2 16.5 28.0* 16.5 17.6 
ASA physical status 
ASA 2 50  49  62  44  49  
ASA 3 48  50  38  55  49  
ASA 4 2  1  0  1  1  
Past medical history 
Pulmonary disease 35  30  38  33  33  
Asthma 5  5  3  3  4  
Smoking history 9  7  19  8  9  
Cardiac disease 5  4  11  8  6  
Renal disease 0  3  8  5  3  
CNS disease 7  3  3  14  7  
No. hospitalizations in past year 
None 27  20  24  18  22  
1-4 64  68  57  67  65  
5+ 8  13  19  15  13  
Average days hospitalized 7.1 8.4 8.9 9.7 8.4 
Transfusion history 
No prior transfusions 22  25  22  18  22  
<= 10 prior transfusions 54  53  57  56  54  
> 10 prior transfusions 24  23  22  26  24  
Alloimmunized 19  10  19  11  14  
Previous transfusion reactions 5  4  5  8  6  
Preoperative screening labs 
Preoperative hypoxia 3  6  4  2  4  
Abnormal CXR 12  7  10  18  11  
Abnormal SGPT (>60 U/L) 16  17  21  31  21  
Creatinine > 1.5 mg/dL 4  5  3  2  4  

Abbreviations: Tx, transfusion; CNS, central nervous system; CXR, chest x-ray; SGPT, serum glutamate pyruvate transaminase.

*

P ≤ .0001.

ASA physical status scores range from 1 to 5, from healthy to preterminal preoperative conditions.9