Results of Cytogenetic Analysis in 31 Cases of MCL
| Result . | No. of Cases . |
|---|---|
| t(11; 14)(q13; q32) present6-150 | 14 |
| t(11; 14)(q13; q32) absent, but karyotype abnormal | 4 |
| Case no. 1: 43-44,X,−Y,der(3)t(3; ?)(p11; ?),t(8; 9)(q24; q13), der(9)t(9; 14)(q13; q32),−11,−15,del(14)(q23), der(17)t(3; 17)(q13; p11),−21,+mar[cp16] | |
| Case no. 2: 47,X,−Y,+3,add(14)(q32),+mar1,+mar2[7] | |
| Case no. 3 and 4: complex abnormal cell lines6-151 | |
| Analysis unsuccessful6-152 | 13 |
| Result . | No. of Cases . |
|---|---|
| t(11; 14)(q13; q32) present6-150 | 14 |
| t(11; 14)(q13; q32) absent, but karyotype abnormal | 4 |
| Case no. 1: 43-44,X,−Y,der(3)t(3; ?)(p11; ?),t(8; 9)(q24; q13), der(9)t(9; 14)(q13; q32),−11,−15,del(14)(q23), der(17)t(3; 17)(q13; p11),−21,+mar[cp16] | |
| Case no. 2: 47,X,−Y,+3,add(14)(q32),+mar1,+mar2[7] | |
| Case no. 3 and 4: complex abnormal cell lines6-151 | |
| Analysis unsuccessful6-152 | 13 |
Includes 1 case with complex disruption of both 11q13 and 14q32 but no clearly identifiable translocation.
Patients with concurrent breast cancer in lymph node specimens. Abnormal karyotype is likely that of carcinoma.
Specimens that failed to yield analyzable metaphases or yielded only normal metaphases from suboptimal tissue sites (eg, BM or PB).