Factor V Leiden and Current Smoking: Separate and Combined Effects on MI
| Current Smoker . | Factor V Genotype . | Patients . | Controls . | OR3-150 . | CI95 . |
|---|---|---|---|---|---|
| No | Wild-type | 21 | 288 | 1 | |
| No | Leiden | 1 | 13 | 1.1 | 0.1-8.5 |
| Yes | Wild-type | 55 | 84 | 9.0 | 5.1-15.7 |
| Yes | Leiden | 7 | 3 | 32.0 | 7.7-133 |
| Current Smoker . | Factor V Genotype . | Patients . | Controls . | OR3-150 . | CI95 . |
|---|---|---|---|---|---|
| No | Wild-type | 21 | 288 | 1 | |
| No | Leiden | 1 | 13 | 1.1 | 0.1-8.5 |
| Yes | Wild-type | 55 | 84 | 9.0 | 5.1-15.7 |
| Yes | Leiden | 7 | 3 | 32.0 | 7.7-133 |
All odds ratios are relative to the reference category, ie, those who did not smoke and did not carry the mutation. Age-adjusted logistic regression led to similar odds ratios.