Table 1.

Predictive Characteristics of Serologic Tests for Platelet Autoantibodies

TestMethodSensitivitySpecificityLikelihood Ratio*
Capture-P Direct 17/46 (37%) 10/15 (67%) 1.1 
Capture-P Indirect 20/46 (43%) 9/15 (60%) 1.1 
CELIA Direct 60/81 (74%) 12/46 (26%) 1.0 
ELISA Indirect 30/88 (34%) 41/53 (77%) 1.5 
MAIPAρ Modified 33/71 (47%) 34/40 (85%) 3.1 
TestMethodSensitivitySpecificityLikelihood Ratio*
Capture-P Direct 17/46 (37%) 10/15 (67%) 1.1 
Capture-P Indirect 20/46 (43%) 9/15 (60%) 1.1 
CELIA Direct 60/81 (74%) 12/46 (26%) 1.0 
ELISA Indirect 30/88 (34%) 41/53 (77%) 1.5 
MAIPAρ Modified 33/71 (47%) 34/40 (85%) 3.1 
*

Likelihood ratio = sensitivity/(1 − specificity).

Competitive enzyme-linked immunoassay for PAIgG (data from Brighton et al3 ).

Enzyme-linked immunosorbant assay for PAIgG (data from Brighton et al3 ).

ρ Modified monoclonal antibody immobilization of platelet antigens (data from Brighton et al3 ).

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