Serum Iron Measures and Leukocyte Vitamin C Levels Before (Day 1) and After (Days 2 and 3) Vitamin C Supplementation
| . | Day 1 . | Day 2 . | Day 3 . | P . |
|---|---|---|---|---|
| Serum iron (μg/dL) | ||||
| Men* | 124 ± 46 | 125 ± 51 | 123 ± 65 | .9 |
| Women* | 101 ± 36 | 104 ± 37 | 104 ± 36 | .96 |
| Total iron binding capacity (μg/dL) | ||||
| Men* | 261 ± 39 | 269 ± 56 | 262 ± 58 | .5 |
| Women* | 288 ± 57 | 289 ± 51 | 281 ± 49 | .2 |
| Transferrin saturation (%) | ||||
| Men* | 48 ± 18 | 47 ± 18 | 47 ± 21 | .99 |
| Women* | 35 ± 10 | 36 ± 11 | 37 ± 12 | .4 |
| Serum ferritin (μg/L)† | ||||
| Men* | 387 (117-1279) | 358 (113-1135) | 346 (111-1076) | .2 |
| Women* | 93 (32-266) | 90 (30-271) | 87 (24-323) | .3 |
| Vitamin C (ng/108 leukocytes) | ||||
| Men‡ | 43 ± 13 | 52 ± 13 | 53 ± 17 | .036 |
| Womenρ | 51 ± 17 | 62 ± 17 | 58 ± 20 | .001 |
| . | Day 1 . | Day 2 . | Day 3 . | P . |
|---|---|---|---|---|
| Serum iron (μg/dL) | ||||
| Men* | 124 ± 46 | 125 ± 51 | 123 ± 65 | .9 |
| Women* | 101 ± 36 | 104 ± 37 | 104 ± 36 | .96 |
| Total iron binding capacity (μg/dL) | ||||
| Men* | 261 ± 39 | 269 ± 56 | 262 ± 58 | .5 |
| Women* | 288 ± 57 | 289 ± 51 | 281 ± 49 | .2 |
| Transferrin saturation (%) | ||||
| Men* | 48 ± 18 | 47 ± 18 | 47 ± 21 | .99 |
| Women* | 35 ± 10 | 36 ± 11 | 37 ± 12 | .4 |
| Serum ferritin (μg/L)† | ||||
| Men* | 387 (117-1279) | 358 (113-1135) | 346 (111-1076) | .2 |
| Women* | 93 (32-266) | 90 (30-271) | 87 (24-323) | .3 |
| Vitamin C (ng/108 leukocytes) | ||||
| Men‡ | 43 ± 13 | 52 ± 13 | 53 ± 17 | .036 |
| Womenρ | 51 ± 17 | 62 ± 17 | 58 ± 20 | .001 |
P represents significance level for repeated measures analysis of variance of mean values over 3 days. Statistical comparison between men and women: serum ferritins differ at significance level of <.0005 and transferrin saturations at level of <.05. Normal ranges: serum iron 60 to 150; total iron binding capacity 250 to 400; transferrin saturation 20 to 50; serum ferritin (see Materials and Methods section); vitamin C ≥20 ng/108 leukocytes.
N = 28 day 1 and 27 days 2 and 3.
Geometric mean and SD range.
N = 22 on day 1 and 20 on days 2 and 3.
ρ N = 21 on day 1 and 20 on days 2 and 3.