Table 1.

Number of Mice, p, Technical Variance, and Correlation Coefficients (r) for the Experimental Groups

Dose (Gy)Mice*B1† pB2 pB3 pTechnical Variancer
B1:B3B2:B3B3:Femur
8.0 80/0 
7.0 91/39 0.722 0.723 0.706 0.0008 0.14 0.75 0.86 
7.0 70/52 0.758  0.770 
6.5 13/12 0.724  0.700 
6.0 23/23 0.762 0.657 0.616 0.0007 0.13 0.76 0.93 
5.5 15/15 0.740  0.677 
5.0 40/40 0.731 0.737 0.797 0.0015 0.75 0.85 0.74 
4.5 15/15 0.710  0.700 
4.0 54/54 0.739 0.737 0.704 0.0016 0.61 0.87 0.69 
3.5 18/18 0.683 0.716 0.658 
3.0 50/50 0.743 0.752 0.724 0.0013 0.74 0.87 0.58 
0.0 30/30 0.719      0.79 
 
      
mean  0.730 0.720 0.705 0.0012 
±SD  ±0.021 ±0.030 ±0.049 ±0.0004 
Dose (Gy)Mice*B1† pB2 pB3 pTechnical Variancer
B1:B3B2:B3B3:Femur
8.0 80/0 
7.0 91/39 0.722 0.723 0.706 0.0008 0.14 0.75 0.86 
7.0 70/52 0.758  0.770 
6.5 13/12 0.724  0.700 
6.0 23/23 0.762 0.657 0.616 0.0007 0.13 0.76 0.93 
5.5 15/15 0.740  0.677 
5.0 40/40 0.731 0.737 0.797 0.0015 0.75 0.85 0.74 
4.5 15/15 0.710  0.700 
4.0 54/54 0.739 0.737 0.704 0.0016 0.61 0.87 0.69 
3.5 18/18 0.683 0.716 0.658 
3.0 50/50 0.743 0.752 0.724 0.0013 0.74 0.87 0.58 
0.0 30/30 0.719      0.79 
 
      
mean  0.730 0.720 0.705 0.0012 
±SD  ±0.021 ±0.030 ±0.049 ±0.0004 
*

Number of mice irradiated/number surviving. Nearly all mice surviving were assayed for blood Pgk ratios. A few samples/mice were lost.

B1, prebleed; B2, 70-day bleed; B3, 130-day bleed.

r is the correlation coefficient relating the measurements of p on the same mice at 2 different time points. r has a range of 0 to 1, with values approaching 0 indicating a lack of correlation between the two groups, while values approaching 1 indicate a strong correlation.

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