Characteristics of Mutations in the 5′ Noncoding Region of BCL-6 in AIDS-NHL
| Sample . | Histology . | Mutation (position)*† . |
|---|---|---|
| 1142 | AIDS-BL | +G (706), Δ‡ T (1098) |
| 1143 | AIDS-BL | T→C (705), T→A (717), G→C (756), ΔT (1104) |
| 1220 | AIDS-BL | T→G (562), G→A (835), +T (1104) |
| PA682 | AIDS-BL | C→A (742), C→T (1079) |
| HBL-2 | AIDS-BL | T→G (469), ΔA (494) |
| BRG-A | AIDS-BL | A→T (658) |
| 674 | AIDS-DLCL | T→G (465), A→G (468) |
| 1139 | AIDS-DLCL | T→A (418), C→A (425), G→A (503), C→A (601), G→A (678) |
| 1141 | AIDS-DLCL | G→A (481), T→C (631), +[TCTTTGGGTTT] (1083) |
| 1156 | AIDS-DLCL | C→A (522), C→A (610), T→G (628), G→A (672) |
| 1221 | AIDS-ALCL | C→A (526) |
| Sample . | Histology . | Mutation (position)*† . |
|---|---|---|
| 1142 | AIDS-BL | +G (706), Δ‡ T (1098) |
| 1143 | AIDS-BL | T→C (705), T→A (717), G→C (756), ΔT (1104) |
| 1220 | AIDS-BL | T→G (562), G→A (835), +T (1104) |
| PA682 | AIDS-BL | C→A (742), C→T (1079) |
| HBL-2 | AIDS-BL | T→G (469), ΔA (494) |
| BRG-A | AIDS-BL | A→T (658) |
| 674 | AIDS-DLCL | T→G (465), A→G (468) |
| 1139 | AIDS-DLCL | T→A (418), C→A (425), G→A (503), C→A (601), G→A (678) |
| 1141 | AIDS-DLCL | G→A (481), T→C (631), +[TCTTTGGGTTT] (1083) |
| 1156 | AIDS-DLCL | C→A (522), C→A (610), T→G (628), G→A (672) |
| 1221 | AIDS-ALCL | C→A (526) |
Abbreviations: AIDS-BL, AIDS-related Burkitt's lymphoma; AIDS-DLCL, AIDS-related diffuse large cell lymphoma; AIDS-ALCL, AIDS-related anaplastic large cell lymphoma.
The first nucleotide of the BCL-6 cDNA is arbitrarily chosen as position +1.
The allelic distribution of mutations could not be defined because of the sequencing strategy adopted.
Δ, deletion.