Sequences of the CRM From Various Signaling Subunits of Cytokine Receptors Are Compared
| CRM: . | βc1 . | βc2 . | LIFR1 . | LIFR2 . | gp130 . | TPOR1 . | TPOR2 . | EPOR . | IL2Rβ . | GHR . | PRLR . |
|---|---|---|---|---|---|---|---|---|---|---|---|
| βc1 | 18.0 | 12.0 | 17.0 | 17.7 | 14.9 | 16.1 | 15.7 | 17.6 | 14.7 | 16.2 | |
| βc2 | 23.2 | 13.7 | 18.4 | 20.8 | 19.8 | 19.1 | 23.1 | 16.3 | 15.3 | 14.0 | |
| LIFR1 | 14.7 | 16.2 | 20.3 | 17.7 | 14.0 | 15.6 | 18.4 | 12.4 | 12.6 | 21.6 | |
| LIFR2 | 15.4 | 16.6 | 19.6 | 29.5 | 11.7 | 15.0 | 18.8 | 16.3 | 13.6 | 18.4 | |
| gp130 | 16.8 | 22.7 | 18.6 | 21.3 | 15.4 | 17.7 | 17.4 | 14.7 | 17.9 | 24.9 | |
| TPOR1 | 16.6 | 16.8 | 14.9 | 12.8 | 16.4 | 19.5 | 28.2 | 14.9 | 18.6 | 21.1 | |
| TPOR2 | 15.7 | 17.5 | 17.2 | 16.9 | 18.8 | 17.2 | 21.3 | 17.4 | 15.5 | 19.7 | |
| EPOR | 15.6 | 20.4 | 15.7 | 18.6 | 19.4 | 26.6 | 20.7 | 18.5 | 17.9 | 19.6 | |
| IL2Rβ | 17.4 | 20.5 | 11.9 | 16.3 | 14.4 | 17.7 | 15.5 | 16.8 | 17.2 | 16.9 | |
| GHR | 15.7 | 18.5 | 13.7 | 15.6 | 21.7 | 21.3 | 17.5 | 18.1 | 14.4 | 32.0 | |
| PRLR | 19.1 | 18.6 | 19.8 | 20.3 | 27.5 | 23.2 | 17.6 | 20.3 | 17.0 | 31.5 |
| CRM: . | βc1 . | βc2 . | LIFR1 . | LIFR2 . | gp130 . | TPOR1 . | TPOR2 . | EPOR . | IL2Rβ . | GHR . | PRLR . |
|---|---|---|---|---|---|---|---|---|---|---|---|
| βc1 | 18.0 | 12.0 | 17.0 | 17.7 | 14.9 | 16.1 | 15.7 | 17.6 | 14.7 | 16.2 | |
| βc2 | 23.2 | 13.7 | 18.4 | 20.8 | 19.8 | 19.1 | 23.1 | 16.3 | 15.3 | 14.0 | |
| LIFR1 | 14.7 | 16.2 | 20.3 | 17.7 | 14.0 | 15.6 | 18.4 | 12.4 | 12.6 | 21.6 | |
| LIFR2 | 15.4 | 16.6 | 19.6 | 29.5 | 11.7 | 15.0 | 18.8 | 16.3 | 13.6 | 18.4 | |
| gp130 | 16.8 | 22.7 | 18.6 | 21.3 | 15.4 | 17.7 | 17.4 | 14.7 | 17.9 | 24.9 | |
| TPOR1 | 16.6 | 16.8 | 14.9 | 12.8 | 16.4 | 19.5 | 28.2 | 14.9 | 18.6 | 21.1 | |
| TPOR2 | 15.7 | 17.5 | 17.2 | 16.9 | 18.8 | 17.2 | 21.3 | 17.4 | 15.5 | 19.7 | |
| EPOR | 15.6 | 20.4 | 15.7 | 18.6 | 19.4 | 26.6 | 20.7 | 18.5 | 17.9 | 19.6 | |
| IL2Rβ | 17.4 | 20.5 | 11.9 | 16.3 | 14.4 | 17.7 | 15.5 | 16.8 | 17.2 | 16.9 | |
| GHR | 15.7 | 18.5 | 13.7 | 15.6 | 21.7 | 21.3 | 17.5 | 18.1 | 14.4 | 32.0 | |
| PRLR | 19.1 | 18.6 | 19.8 | 20.3 | 27.5 | 23.2 | 17.6 | 20.3 | 17.0 | 31.5 |
In the top/right panel, percentage identity of aligned sequences using the Pileup and Distances modules of the University of Wisconsin Genetics Computer Group software86 and in the lower/left panel, the percentage identity determined using ClustalW.87