Demographic and Clinical Features of Chuvash Patients With Polycythemia and Their First-Degree Relatives
| . | Index Subjects . | First-Degree Family Members (N = 12) . | P . |
|---|---|---|---|
| . | (N = 6) . | . | . |
| Age (years) | 11 ± 3 | 33 ± 13 | <.0005 |
| Females (no. and %) | 4 (67) | 6 (50) | .6 |
| Hemoglobin (g/dL) | 22.6 ± 1.4 | 14.5 ± 1.1 | <.0005 |
| Hematocrit (%) | 66.6 ± 3.9 | 42.7 ± 3.4 | <.0005 |
| Red blood cells (×10−6/μL) | 7.5 ± 0.5 | 4.7 ± 0.5 | <.0005 |
| Mean corpuscular volume (fL) | 89 ± 4 | 90 ± 5 | .6 |
| Mean corpuscular hemoglobin (pg) | 30.1 ± 1.3 | 30.6 ± 1 | .5 |
| Red blood cell distribution width (%) | 14.0 ± 0.88-150 | 13.0 ± 0.68-151 | .012 |
| Reticulocytes (×10−3/μL) | 66.3 ± 39.28-152 | 41.7 ± 15.6ρ | .3 |
| White blood cells (×10−3/μL) | 7.2 ± 1.6 | 7.3 ± 1.5 | .8 |
| Neutrophils (×10−3/μL) | 4.1 ± 1.4 | 3.8 ± 1.2 | .7 |
| Lymphocytes (×10−3/μL) | 2.2 ± 1.0 | 2.4 ± 0.9 | .7 |
| Monocytes (×10−3/μL) | 0.6 ± 0.6 | 0.9 ± 0.6 | .4 |
| Eosinophils (×10−3/μL) | 0.2 ± 0.2 | 0.2 ± 0.1 | .6 |
| Platelets (×10−3/μL) | 213 ± 38 | 255 ± 53 | .1 |
| . | Index Subjects . | First-Degree Family Members (N = 12) . | P . |
|---|---|---|---|
| . | (N = 6) . | . | . |
| Age (years) | 11 ± 3 | 33 ± 13 | <.0005 |
| Females (no. and %) | 4 (67) | 6 (50) | .6 |
| Hemoglobin (g/dL) | 22.6 ± 1.4 | 14.5 ± 1.1 | <.0005 |
| Hematocrit (%) | 66.6 ± 3.9 | 42.7 ± 3.4 | <.0005 |
| Red blood cells (×10−6/μL) | 7.5 ± 0.5 | 4.7 ± 0.5 | <.0005 |
| Mean corpuscular volume (fL) | 89 ± 4 | 90 ± 5 | .6 |
| Mean corpuscular hemoglobin (pg) | 30.1 ± 1.3 | 30.6 ± 1 | .5 |
| Red blood cell distribution width (%) | 14.0 ± 0.88-150 | 13.0 ± 0.68-151 | .012 |
| Reticulocytes (×10−3/μL) | 66.3 ± 39.28-152 | 41.7 ± 15.6ρ | .3 |
| White blood cells (×10−3/μL) | 7.2 ± 1.6 | 7.3 ± 1.5 | .8 |
| Neutrophils (×10−3/μL) | 4.1 ± 1.4 | 3.8 ± 1.2 | .7 |
| Lymphocytes (×10−3/μL) | 2.2 ± 1.0 | 2.4 ± 0.9 | .7 |
| Monocytes (×10−3/μL) | 0.6 ± 0.6 | 0.9 ± 0.6 | .4 |
| Eosinophils (×10−3/μL) | 0.2 ± 0.2 | 0.2 ± 0.1 | .6 |
| Platelets (×10−3/μL) | 213 ± 38 | 255 ± 53 | .1 |