Comparison of Clinical Features and Outcomes
| Factor . | BCLCL (N = 492) . | PTCL (N = 68) . | P Value . |
|---|---|---|---|
| Mean age (yr) | 54% | 52% | NS |
| Age >60 yr | 43% | 38% | NS |
| Stage 3 or 4 | 48% | 74% | <.001 |
| B symptoms | 28% | 56% | <.001 |
| Extranodal disease >1 | 15% | 16% | NS |
| PS >1 | 15% | 21% | NS |
| LDH elevated | 44% | 59% | .02 |
| β2M >3.0 mg/dL | 26% | 46% | .001 |
| IPI 0 or 1 | 46% | 34% | |
| IPI 2 | 25% | 35% | |
| IPI 3 | 18% | 13% | |
| IPI >3 | 11% | 18% | |
| MDATS 0 or 1 | 40% | 25% | |
| MDATS 2 | 15% | 18% | |
| MDATS 3 | 20% | 27% | |
| MDATS > 3 | 25% | 30% | |
| CR rate | 76% | 65% | .04 |
| 5-yr FFS | 56% | 38% | <.001 |
| 5-yr OS | 63% | 39% | <.001 |
| IPI >2 CR rate | 60% | 43% | .15 |
| IPI <3 CR rate | 83% | 75% | .15 |
| IPI >2 5-yr FFS | 35% | 11% | .044 |
| IPI <3 5-yr FFS | 64% | 49% | .001 |
| IPI >2 5-yr OS | 40% | 10% | .011 |
| IPI <3 5-yr OS | 71% | 55% | .013 |
| MDATS >2 CR rate | 61% | 53% | .33 |
| MDATS <3 CR rate | 88% | 80% | .22 |
| MDATS >2 5-yr FFS | 37% | 25% | .032 |
| MDATS <3 5-yr FFS | 70% | 56% | .007 |
| MDATS >2 5-yr OS | 41% | 24% | .026 |
| Factor . | BCLCL (N = 492) . | PTCL (N = 68) . | P Value . |
|---|---|---|---|
| Mean age (yr) | 54% | 52% | NS |
| Age >60 yr | 43% | 38% | NS |
| Stage 3 or 4 | 48% | 74% | <.001 |
| B symptoms | 28% | 56% | <.001 |
| Extranodal disease >1 | 15% | 16% | NS |
| PS >1 | 15% | 21% | NS |
| LDH elevated | 44% | 59% | .02 |
| β2M >3.0 mg/dL | 26% | 46% | .001 |
| IPI 0 or 1 | 46% | 34% | |
| IPI 2 | 25% | 35% | |
| IPI 3 | 18% | 13% | |
| IPI >3 | 11% | 18% | |
| MDATS 0 or 1 | 40% | 25% | |
| MDATS 2 | 15% | 18% | |
| MDATS 3 | 20% | 27% | |
| MDATS > 3 | 25% | 30% | |
| CR rate | 76% | 65% | .04 |
| 5-yr FFS | 56% | 38% | <.001 |
| 5-yr OS | 63% | 39% | <.001 |
| IPI >2 CR rate | 60% | 43% | .15 |
| IPI <3 CR rate | 83% | 75% | .15 |
| IPI >2 5-yr FFS | 35% | 11% | .044 |
| IPI <3 5-yr FFS | 64% | 49% | .001 |
| IPI >2 5-yr OS | 40% | 10% | .011 |
| IPI <3 5-yr OS | 71% | 55% | .013 |
| MDATS >2 CR rate | 61% | 53% | .33 |
| MDATS <3 CR rate | 88% | 80% | .22 |
| MDATS >2 5-yr FFS | 37% | 25% | .032 |
| MDATS <3 5-yr FFS | 70% | 56% | .007 |
| MDATS >2 5-yr OS | 41% | 24% | .026 |
Abbreviation: NS, not significant.