Table 2. HPLC of Hb From Transgenic... | American Society of Hematology

Table 2.

HPLC of Hb From Transgenic Sickle Cell Mice

Peak Tetramers	Percentage of Total Hb
	M-Tg98Ru	M-Tg58Ru	Tg58 × Tg98
	(N = 7)^*	(N = 9)^*	(N = 23)^*
1. mα^g2₂mβ^s2₂	21.0 ± 0.1^†	18.5 ± 0.8	12.1 ± 0.1
2. mα^g2₂mβ^s₂	9.2 ± 0.1	7.8 ± 0.2	4.6 ± 0.1
3. mα^a₂mβ^s2₂	15.5 ± 0.1	17.9 ± 0.4	9.8 ± 0.1
4. mα^g2₂hβ^SAnt₂	6.7 ± 0.1	12.7 ± 0.2	8.7 ± 0.2
5. mα^a₂mβ^s₂hα₂mβ^s2₂	21.1 ± 0.2	16.8 ± 0.3	16.5 ± 0.2^‡
6. mα^a₂hβ^SAnt₂hα₂mβ^s₂	13.3 ± 0.1	10.7 ± 0.3	10.4 ± 0.1
7. hα₂hβ^SAnt₂	13.4 ± 0.3	15.7 ± 0.6	37.9 ± 0.3

Peak Tetramers	Percentage of Total Hb
	M-Tg98Ru	M-Tg58Ru	Tg58 × Tg98
	(N = 7)^*	(N = 9)^*	(N = 23)^*
1. mα^g2₂mβ^s2₂	21.0 ± 0.1^†	18.5 ± 0.8	12.1 ± 0.1
2. mα^g2₂mβ^s₂	9.2 ± 0.1	7.8 ± 0.2	4.6 ± 0.1
3. mα^a₂mβ^s2₂	15.5 ± 0.1	17.9 ± 0.4	9.8 ± 0.1
4. mα^g2₂hβ^SAnt₂	6.7 ± 0.1	12.7 ± 0.2	8.7 ± 0.2
5. mα^a₂mβ^s₂hα₂mβ^s2₂	21.1 ± 0.2	16.8 ± 0.3	16.5 ± 0.2^‡
6. mα^a₂hβ^SAnt₂hα₂mβ^s₂	13.3 ± 0.1	10.7 ± 0.3	10.4 ± 0.1
7. hα₂hβ^SAnt₂	13.4 ± 0.3	15.7 ± 0.6	37.9 ± 0.3

Number of analyses.

Mean ± SEM.

Peaks 5 and 6 each contain two Hb tetrameters.