Table 1. B-Cell Proliferation Induced by... | American Society of Hematology

Table 1.

B-Cell Proliferation Induced by Various Stimuli In Vitro

	[³H]-TdR Incorporation^* (cpm)	Response in Telomerase Activity^† (%)
Medium	573 ± 68	Not detectable
Anti-IgM (10 μg/mL)	1,652 ± 473	0.2
Anti-IgM-Beads (10 μg/mL)	7,267 ± 77	115.5
Anti-IgM + anti-CD40 (10 μg/mL)	6,716 ± 290	100
Anti-IgM + IL-2 (100 U/mL)	6,228 ± 314	32.7
Anti-IgM + IL-4 (0.5 U/mL)	6,608 ± 793	84.3
Anti-IgM + IL-6 (100 U/mL)	990 ± 106	0.4
Anti-IgM + IL-13 (10 ng/mL)	6,398 ± 524	62.1

	[³H]-TdR Incorporation^* (cpm)	Response in Telomerase Activity^† (%)
Medium	573 ± 68	Not detectable
Anti-IgM (10 μg/mL)	1,652 ± 473	0.2
Anti-IgM-Beads (10 μg/mL)	7,267 ± 77	115.5
Anti-IgM + anti-CD40 (10 μg/mL)	6,716 ± 290	100
Anti-IgM + IL-2 (100 U/mL)	6,228 ± 314	32.7
Anti-IgM + IL-4 (0.5 U/mL)	6,608 ± 793	84.3
Anti-IgM + IL-6 (100 U/mL)	990 ± 106	0.4
Anti-IgM + IL-13 (10 ng/mL)	6,398 ± 524	62.1

Mean cpm ± SD (n = 3).

†

Percentage response in telomerase activity was determined by densitometric measurement with image analyzer. Percentage activity was calculated as the relative intensity in comparison to the maximum response (anti-IgM Ab + anti-CD40 MoAb).

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